Prostaglandin E receptors in regulation of blood pressure

Yi Fei Miao; Ji Hong Kang; Ji Chun Yang; You Fei Guan

Prostaglandin E receptors in regulation of blood pressure

Yi Fei Miao^*
, Ji Hong Kang
, Ji Chun Yang
, You Fei Guan

^*Corresponding author for this work

Unknown

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Prostaglandin E₂ (PGE₂) is one of the major metabolic products of arachidonic acid. PGE₂ plays important roles in various important physiological processes by binding to its C protein-coupled receptors designated EP1, EP2, EP3, and EP4, respectively. EP receptors are highly expressed in the kidney and cardiovascular system, and PGE₂-mediated activation of EP receptors plays important roles in the regulation of blood pressure. The abnormal expression of EP receptors in the kidney and cardiovascular system is associated with some blood pressure disease such as salt-sensitive hypertension, renal hypertension, and myocardial hypertrophy.

Original language	English
Pages (from-to)	424+425-427
Journal	Chinese Pharmacological Bulletin
Volume	26
Issue number	4
State	Published - Apr 2010
Externally published	Yes

Keywords

Blood pressure
Myocardial hypertrophy
Prostaglandin E
Prostaglandin E receptors
Prostaglandins
Salt-sensitive hypertension

Cite this

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title = "Prostaglandin E receptors in regulation of blood pressure",

abstract = "Prostaglandin E2 (PGE2) is one of the major metabolic products of arachidonic acid. PGE2 plays important roles in various important physiological processes by binding to its C protein-coupled receptors designated EP1, EP2, EP3, and EP4, respectively. EP receptors are highly expressed in the kidney and cardiovascular system, and PGE2-mediated activation of EP receptors plays important roles in the regulation of blood pressure. The abnormal expression of EP receptors in the kidney and cardiovascular system is associated with some blood pressure disease such as salt-sensitive hypertension, renal hypertension, and myocardial hypertrophy.",

keywords = "Blood pressure, Myocardial hypertrophy, Prostaglandin E, Prostaglandin E receptors, Prostaglandins, Salt-sensitive hypertension",

author = "Miao, \{Yi Fei\} and Kang, \{Ji Hong\} and Yang, \{Ji Chun\} and Guan, \{You Fei\}",

year = "2010",

month = apr,

language = "英语",

volume = "26",

pages = "424+425--427",

journal = "Chinese Pharmacological Bulletin",

issn = "1001-1978",

publisher = "Institute of Clinical Pharmacology",

number = "4",

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TY - JOUR

T1 - Prostaglandin E receptors in regulation of blood pressure

AU - Miao, Yi Fei

AU - Kang, Ji Hong

AU - Yang, Ji Chun

AU - Guan, You Fei

PY - 2010/4

Y1 - 2010/4

N2 - Prostaglandin E2 (PGE2) is one of the major metabolic products of arachidonic acid. PGE2 plays important roles in various important physiological processes by binding to its C protein-coupled receptors designated EP1, EP2, EP3, and EP4, respectively. EP receptors are highly expressed in the kidney and cardiovascular system, and PGE2-mediated activation of EP receptors plays important roles in the regulation of blood pressure. The abnormal expression of EP receptors in the kidney and cardiovascular system is associated with some blood pressure disease such as salt-sensitive hypertension, renal hypertension, and myocardial hypertrophy.

AB - Prostaglandin E2 (PGE2) is one of the major metabolic products of arachidonic acid. PGE2 plays important roles in various important physiological processes by binding to its C protein-coupled receptors designated EP1, EP2, EP3, and EP4, respectively. EP receptors are highly expressed in the kidney and cardiovascular system, and PGE2-mediated activation of EP receptors plays important roles in the regulation of blood pressure. The abnormal expression of EP receptors in the kidney and cardiovascular system is associated with some blood pressure disease such as salt-sensitive hypertension, renal hypertension, and myocardial hypertrophy.

KW - Blood pressure

KW - Myocardial hypertrophy

KW - Prostaglandin E

KW - Prostaglandin E receptors

KW - Prostaglandins

KW - Salt-sensitive hypertension

UR - https://www.scopus.com/pages/publications/77953877972

M3 - 文章

AN - SCOPUS:77953877972

SN - 1001-1978

VL - 26

SP - 424+425-427

JO - Chinese Pharmacological Bulletin

JF - Chinese Pharmacological Bulletin

IS - 4

ER -

Prostaglandin E receptors in regulation of blood pressure

Abstract

Keywords

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