Probing cytotoxicity of CdSe and CdSe/CdS quantum dots

Yan Jie Bao; Jun Jun Li; Yi Ting Wang; Lei Yu; Lei Lou; Wei Ji Du; Zi Qiang Zhu; Hui Peng; Jian Zhong Zhu

doi:10.1016/j.cclet.2010.12.008

Probing cytotoxicity of CdSe and CdSe/CdS quantum dots

Yan Jie Bao
, Jun Jun Li
, Yi Ting Wang
, Lei Yu
, Lei Lou
, Wei Ji Du
, Zi Qiang Zhu
, Hui Peng
, Jian Zhong Zhu

School of Physics and Electronic Science

East China Normal University

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Toxicities of CdSe and CdSe/CdS quantum dots (QDs) synthesized by ultrasound-assisted methods were investigated in vitro and in vivo. Five human cell lines were used to assess the cytotoxicity of as-prepared CdSe and CdSe/CdS by assays of MTT viability, red blood cell hemolysis, flow cytometry, and fluorescence imaging. The results show that these QDs may be cytotoxic by their influence in S and G2 phases in cell cycles. The cytotoxicity of QDs depends on both the physicochemical properties and related to target cells.

Original language	English
Pages (from-to)	843-846
Number of pages	4
Journal	Chinese Chemical Letters
Volume	22
Issue number	7
DOIs	https://doi.org/10.1016/j.cclet.2010.12.008
State	Published - Jul 2011

Keywords

CdSe
CdSe/CdS
Cell
Cytotoxicity
Quantum dots

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10.1016/j.cclet.2010.12.008

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title = "Probing cytotoxicity of CdSe and CdSe/CdS quantum dots",

abstract = "Toxicities of CdSe and CdSe/CdS quantum dots (QDs) synthesized by ultrasound-assisted methods were investigated in vitro and in vivo. Five human cell lines were used to assess the cytotoxicity of as-prepared CdSe and CdSe/CdS by assays of MTT viability, red blood cell hemolysis, flow cytometry, and fluorescence imaging. The results show that these QDs may be cytotoxic by their influence in S and G2 phases in cell cycles. The cytotoxicity of QDs depends on both the physicochemical properties and related to target cells.",

keywords = "CdSe, CdSe/CdS, Cell, Cytotoxicity, Quantum dots",

author = "Bao, \{Yan Jie\} and Li, \{Jun Jun\} and Wang, \{Yi Ting\} and Lei Yu and Lei Lou and Du, \{Wei Ji\} and Zhu, \{Zi Qiang\} and Hui Peng and Zhu, \{Jian Zhong\}",

year = "2011",

month = jul,

doi = "10.1016/j.cclet.2010.12.008",

language = "英语",

volume = "22",

pages = "843--846",

journal = "Chinese Chemical Letters",

issn = "1001-8417",

publisher = "Elsevier B.V.",

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TY - JOUR

T1 - Probing cytotoxicity of CdSe and CdSe/CdS quantum dots

AU - Bao, Yan Jie

AU - Li, Jun Jun

AU - Wang, Yi Ting

AU - Yu, Lei

AU - Lou, Lei

AU - Du, Wei Ji

AU - Zhu, Zi Qiang

AU - Peng, Hui

AU - Zhu, Jian Zhong

PY - 2011/7

Y1 - 2011/7

N2 - Toxicities of CdSe and CdSe/CdS quantum dots (QDs) synthesized by ultrasound-assisted methods were investigated in vitro and in vivo. Five human cell lines were used to assess the cytotoxicity of as-prepared CdSe and CdSe/CdS by assays of MTT viability, red blood cell hemolysis, flow cytometry, and fluorescence imaging. The results show that these QDs may be cytotoxic by their influence in S and G2 phases in cell cycles. The cytotoxicity of QDs depends on both the physicochemical properties and related to target cells.

AB - Toxicities of CdSe and CdSe/CdS quantum dots (QDs) synthesized by ultrasound-assisted methods were investigated in vitro and in vivo. Five human cell lines were used to assess the cytotoxicity of as-prepared CdSe and CdSe/CdS by assays of MTT viability, red blood cell hemolysis, flow cytometry, and fluorescence imaging. The results show that these QDs may be cytotoxic by their influence in S and G2 phases in cell cycles. The cytotoxicity of QDs depends on both the physicochemical properties and related to target cells.

KW - CdSe

KW - CdSe/CdS

KW - Cell

KW - Cytotoxicity

KW - Quantum dots

UR - https://www.scopus.com/pages/publications/79957453175

U2 - 10.1016/j.cclet.2010.12.008

DO - 10.1016/j.cclet.2010.12.008

M3 - 文章

AN - SCOPUS:79957453175

SN - 1001-8417

VL - 22

SP - 843

EP - 846

JO - Chinese Chemical Letters

JF - Chinese Chemical Letters

IS - 7

ER -

Probing cytotoxicity of CdSe and CdSe/CdS quantum dots

Abstract

Keywords

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