Preparation of poly(vinylpyrrolidone)-protected Prussian blue nanoparticles-modified electrode and its electrocatalytic reduction for hemoglobin

Yuezhong Xian; Yuyan Zhou; Yang Xian; Lihui Zhou; Haiting Wang; Litong Jin

doi:10.1016/j.aca.2005.04.090

Preparation of poly(vinylpyrrolidone)-protected Prussian blue nanoparticles-modified electrode and its electrocatalytic reduction for hemoglobin

Yuezhong Xian
, Yuyan Zhou
, Yang Xian
, Lihui Zhou
, Haiting Wang
, Litong Jin^*

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University
East China University of Science and Technology

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

In this paper, a novel modified electrode was developed by using highly dispersed Prussian blue (PB) nanoparticles protected by poly(vinylpyrrolidone) (PVP). The size of the nanoparticles was controlled through adjusting the feed ratio of PVP/Fe²⁺. Physical characteristics of the nanocomposite were studied by transmission electron microscopy (TEM), UV-vis, IR spectroscopy, and X-ray powder diffraction (XRPD) analysis. The electrocatalytic reduction of hemoglobin (Hb) at PVP-protected PB nanoparticles (PVP/PB NPs)-modified electrode had been investigated. In addition, the size effects and biocompatibility of PVP/PB NPs for the electrochemistry of Hb were also observed. Experimental results indicated that the reduction peak currents of Hb were linear with its concentrations over the range from 1.0 × 10 ^-7 to 1.2 × 10^-5 mol/L and the calculated detection limit (S/N = 3) was 4.0 × 10^-8 mol/L.

Original language	English
Pages (from-to)	139-146
Number of pages	8
Journal	Analytica Chimica Acta
Volume	546
Issue number	2
DOIs	https://doi.org/10.1016/j.aca.2005.04.090
State	Published - 8 Aug 2005

Keywords

Electrochemical catalysis
Hemoglobin (Hb)
Poly(vinylpyrrolidone) (PVP)
Prussian blue (PB) nanoparticles

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10.1016/j.aca.2005.04.090

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title = "Preparation of poly(vinylpyrrolidone)-protected Prussian blue nanoparticles-modified electrode and its electrocatalytic reduction for hemoglobin",

abstract = "In this paper, a novel modified electrode was developed by using highly dispersed Prussian blue (PB) nanoparticles protected by poly(vinylpyrrolidone) (PVP). The size of the nanoparticles was controlled through adjusting the feed ratio of PVP/Fe2+. Physical characteristics of the nanocomposite were studied by transmission electron microscopy (TEM), UV-vis, IR spectroscopy, and X-ray powder diffraction (XRPD) analysis. The electrocatalytic reduction of hemoglobin (Hb) at PVP-protected PB nanoparticles (PVP/PB NPs)-modified electrode had been investigated. In addition, the size effects and biocompatibility of PVP/PB NPs for the electrochemistry of Hb were also observed. Experimental results indicated that the reduction peak currents of Hb were linear with its concentrations over the range from 1.0 × 10 -7 to 1.2 × 10-5 mol/L and the calculated detection limit (S/N = 3) was 4.0 × 10-8 mol/L.",

keywords = "Electrochemical catalysis, Hemoglobin (Hb), Poly(vinylpyrrolidone) (PVP), Prussian blue (PB) nanoparticles",

author = "Yuezhong Xian and Yuyan Zhou and Yang Xian and Lihui Zhou and Haiting Wang and Litong Jin",

year = "2005",

month = aug,

day = "8",

doi = "10.1016/j.aca.2005.04.090",

language = "英语",

volume = "546",

pages = "139--146",

journal = "Analytica Chimica Acta",

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TY - JOUR

T1 - Preparation of poly(vinylpyrrolidone)-protected Prussian blue nanoparticles-modified electrode and its electrocatalytic reduction for hemoglobin

AU - Xian, Yuezhong

AU - Zhou, Yuyan

AU - Xian, Yang

AU - Zhou, Lihui

AU - Wang, Haiting

AU - Jin, Litong

PY - 2005/8/8

Y1 - 2005/8/8

N2 - In this paper, a novel modified electrode was developed by using highly dispersed Prussian blue (PB) nanoparticles protected by poly(vinylpyrrolidone) (PVP). The size of the nanoparticles was controlled through adjusting the feed ratio of PVP/Fe2+. Physical characteristics of the nanocomposite were studied by transmission electron microscopy (TEM), UV-vis, IR spectroscopy, and X-ray powder diffraction (XRPD) analysis. The electrocatalytic reduction of hemoglobin (Hb) at PVP-protected PB nanoparticles (PVP/PB NPs)-modified electrode had been investigated. In addition, the size effects and biocompatibility of PVP/PB NPs for the electrochemistry of Hb were also observed. Experimental results indicated that the reduction peak currents of Hb were linear with its concentrations over the range from 1.0 × 10 -7 to 1.2 × 10-5 mol/L and the calculated detection limit (S/N = 3) was 4.0 × 10-8 mol/L.

AB - In this paper, a novel modified electrode was developed by using highly dispersed Prussian blue (PB) nanoparticles protected by poly(vinylpyrrolidone) (PVP). The size of the nanoparticles was controlled through adjusting the feed ratio of PVP/Fe2+. Physical characteristics of the nanocomposite were studied by transmission electron microscopy (TEM), UV-vis, IR spectroscopy, and X-ray powder diffraction (XRPD) analysis. The electrocatalytic reduction of hemoglobin (Hb) at PVP-protected PB nanoparticles (PVP/PB NPs)-modified electrode had been investigated. In addition, the size effects and biocompatibility of PVP/PB NPs for the electrochemistry of Hb were also observed. Experimental results indicated that the reduction peak currents of Hb were linear with its concentrations over the range from 1.0 × 10 -7 to 1.2 × 10-5 mol/L and the calculated detection limit (S/N = 3) was 4.0 × 10-8 mol/L.

KW - Electrochemical catalysis

KW - Hemoglobin (Hb)

KW - Poly(vinylpyrrolidone) (PVP)

KW - Prussian blue (PB) nanoparticles

UR - https://www.scopus.com/pages/publications/22044441226

U2 - 10.1016/j.aca.2005.04.090

DO - 10.1016/j.aca.2005.04.090

M3 - 文章

AN - SCOPUS:22044441226

SN - 0003-2670

VL - 546

SP - 139

EP - 146

JO - Analytica Chimica Acta

JF - Analytica Chimica Acta

IS - 2

ER -

Preparation of poly(vinylpyrrolidone)-protected Prussian blue nanoparticles-modified electrode and its electrocatalytic reduction for hemoglobin

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Keywords

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