TY - JOUR
T1 - Preparation of poly(vinylpyrrolidone)-protected Prussian blue nanoparticles-modified electrode and its electrocatalytic reduction for hemoglobin
AU - Xian, Yuezhong
AU - Zhou, Yuyan
AU - Xian, Yang
AU - Zhou, Lihui
AU - Wang, Haiting
AU - Jin, Litong
PY - 2005/8/8
Y1 - 2005/8/8
N2 - In this paper, a novel modified electrode was developed by using highly dispersed Prussian blue (PB) nanoparticles protected by poly(vinylpyrrolidone) (PVP). The size of the nanoparticles was controlled through adjusting the feed ratio of PVP/Fe2+. Physical characteristics of the nanocomposite were studied by transmission electron microscopy (TEM), UV-vis, IR spectroscopy, and X-ray powder diffraction (XRPD) analysis. The electrocatalytic reduction of hemoglobin (Hb) at PVP-protected PB nanoparticles (PVP/PB NPs)-modified electrode had been investigated. In addition, the size effects and biocompatibility of PVP/PB NPs for the electrochemistry of Hb were also observed. Experimental results indicated that the reduction peak currents of Hb were linear with its concentrations over the range from 1.0 × 10 -7 to 1.2 × 10-5 mol/L and the calculated detection limit (S/N = 3) was 4.0 × 10-8 mol/L.
AB - In this paper, a novel modified electrode was developed by using highly dispersed Prussian blue (PB) nanoparticles protected by poly(vinylpyrrolidone) (PVP). The size of the nanoparticles was controlled through adjusting the feed ratio of PVP/Fe2+. Physical characteristics of the nanocomposite were studied by transmission electron microscopy (TEM), UV-vis, IR spectroscopy, and X-ray powder diffraction (XRPD) analysis. The electrocatalytic reduction of hemoglobin (Hb) at PVP-protected PB nanoparticles (PVP/PB NPs)-modified electrode had been investigated. In addition, the size effects and biocompatibility of PVP/PB NPs for the electrochemistry of Hb were also observed. Experimental results indicated that the reduction peak currents of Hb were linear with its concentrations over the range from 1.0 × 10 -7 to 1.2 × 10-5 mol/L and the calculated detection limit (S/N = 3) was 4.0 × 10-8 mol/L.
KW - Electrochemical catalysis
KW - Hemoglobin (Hb)
KW - Poly(vinylpyrrolidone) (PVP)
KW - Prussian blue (PB) nanoparticles
UR - https://www.scopus.com/pages/publications/22044441226
U2 - 10.1016/j.aca.2005.04.090
DO - 10.1016/j.aca.2005.04.090
M3 - 文章
AN - SCOPUS:22044441226
SN - 0003-2670
VL - 546
SP - 139
EP - 146
JO - Analytica Chimica Acta
JF - Analytica Chimica Acta
IS - 2
ER -