PPAR-γ agonists and diabetic nephropathy

Yahua Zhang; Youfei Guan

doi:10.1007/s11892-005-0057-5

PPAR-γ agonists and diabetic nephropathy

Yahua Zhang, Youfei Guan

Vanderbilt University

Research output: Contribution to journal › Review article › peer-review

23 Scopus citations

Abstract

Diabetic nephropathy is a clinical syndrome of albuminuria, declining glomerular filtration rate, and increased risk of cardiovascular disease. Multiple mechanisms have been implicated in its pathogenesis. Although current therapies appear to be effective, treatment of diabetic nephropathy remains suboptimal. This review summarizes the recently emerging evidence suggesting that peroxisome proliferator-activated receptor-γ agonists may prove to be effective therapeutic agents in the treatment of diabetic renal complications.

Original language	English
Pages (from-to)	470-475
Number of pages	6
Journal	Current Diabetes Reports
Volume	5
Issue number	6
DOIs	https://doi.org/10.1007/s11892-005-0057-5
State	Published - Dec 2005
Externally published	Yes

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title = "PPAR-γ agonists and diabetic nephropathy",

abstract = "Diabetic nephropathy is a clinical syndrome of albuminuria, declining glomerular filtration rate, and increased risk of cardiovascular disease. Multiple mechanisms have been implicated in its pathogenesis. Although current therapies appear to be effective, treatment of diabetic nephropathy remains suboptimal. This review summarizes the recently emerging evidence suggesting that peroxisome proliferator-activated receptor-γ agonists may prove to be effective therapeutic agents in the treatment of diabetic renal complications.",

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AU - Guan, Youfei

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AB - Diabetic nephropathy is a clinical syndrome of albuminuria, declining glomerular filtration rate, and increased risk of cardiovascular disease. Multiple mechanisms have been implicated in its pathogenesis. Although current therapies appear to be effective, treatment of diabetic nephropathy remains suboptimal. This review summarizes the recently emerging evidence suggesting that peroxisome proliferator-activated receptor-γ agonists may prove to be effective therapeutic agents in the treatment of diabetic renal complications.

UR - https://www.scopus.com/pages/publications/29644432906

U2 - 10.1007/s11892-005-0057-5

DO - 10.1007/s11892-005-0057-5

M3 - 文献综述

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AN - SCOPUS:29644432906

SN - 1534-4827

VL - 5

SP - 470

EP - 475

JO - Current Diabetes Reports

JF - Current Diabetes Reports

IS - 6

ER -

PPAR-γ agonists and diabetic nephropathy

Abstract

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