Abstract
A novel oligonucleotide chip with porous silicon / oxidized porous silicon (PS/OPS) as its substrate has been developed. The attachment rate and detection sensitivity were improved obviously due to enormous surface area of PS/OPS compared to the existing conventional techniques. No dependence of storage condition on the detection sensitivity is found (signals variation is within SD). Stability of the oligonucleotide chips is good.
| Original language | English |
|---|---|
| Article number | 124 |
| Pages (from-to) | 535-538 |
| Number of pages | 4 |
| Journal | Proceedings of SPIE - The International Society for Optical Engineering |
| Volume | 5774 |
| DOIs | |
| State | Published - 2005 |
| Event | Fifth International Conference on Thin Film Physics and Applications - Shanghai, China Duration: 31 May 2004 → 2 Jun 2004 |
Keywords
- Attachment rate
- DNA
- Detection sensitivity
- OPS
- Oligonucleotide chip
- PS
- Porous silicon
- Stability
- Substrate