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Polymorphism of DYS287 on Y chromosome in 28 ethnic populations of China

  • Yang Chen
  • , Jia You Chu*
  • , Jian Kun Yu
  • , Liang Yu
  • , Hao Sun
  • , Ke Qin Lin
  • , Yu Fen Tao
  • , Lei Shi
  • , Xiao Qin Huang
  • , Tie Liu Shi
  • , Song Bin Fu
  • *Corresponding author for this work
  • Institute of Medical Biology, Chinese Academy of Medical Sciences & Peking Union Medical College
  • CAS - Shanghai Institute of Nutrition and Health
  • Harbin Medical University

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To investigate the polymorphism of DYS287 among 28 ethnic populations in 9 provinces of China. Method: YAP element was detected by Touchdown PCR amplification and 2% agarose gel electrophoresis. Results: YAP + frequencies in these ethnic populations were as follows: Zang 36.7%, Tu 23.8%, Yi 18.4%, Pumi 11.3%, Tajik 7.4%, Bai 6.7%, Jino 5.1%, Shandong Han 4%, Mulao 2.7%, and Maonan 1.3%. The rest ethnic populations in our study, including Gansu Han, Yunnan Han, Zhuangzu, Daizu, Lizu, Nuzu, Lisu, Naxi, Lahu, Dulong, Hani, Shezu, Weiwuer, Sala, Kerkizi, Dongxiang, Vazu, and Korea didn't carry YAP + element. Conclus ions: Zangzu, Tuzu, Yizu, Pumi, Jino, and Baizu, which belong to Sino-Tibetan language family, carry a high YAP + frequency. Sala, Tuzu, and Tajik, regarded as Central Asia by origin in history and linguistics, also have a high YAP + frequency. Mulao and Maonan, which origin from "Baiyue" ancient ethnic groups, also have a considerable YAP + frequency.

Original languageEnglish
Pages (from-to)196-201
Number of pages6
JournalActa Academiae Medicinae Sinicae
Volume28
Issue number2
StatePublished - Apr 2006
Externally publishedYes

Keywords

  • Polymorphism
  • Y chromosome
  • Y chromosome Alu insertion polymorphism

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