Plasmon resonance scattering spectroscopy at the single-nanoparticle level: Real-time monitoring of a click reaction

Lei Shi, Chao Jing, Wei Ma, Da Wei Li, Jonathan E. Halls, Frank Marken, Yi Tao Long*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

184 Scopus citations

Abstract

A method based on plasmon resonance Rayleigh scattering (PRRS) spectroscopy and dark-field microscopy (DFM) was established for the real-time monitoring of a click reaction at the single-nanoparticle level. Click reactions on the surface of single gold nanoparticles (GNPs) result in interparticle coupling, which leads to a red-shift of the λmax (Δλ max=43nm) in the PRRS spectra and a color change of the single gold nanoparticles in DFM (from green to orange).

Original languageEnglish
Pages (from-to)6011-6014
Number of pages4
JournalAngewandte Chemie - International Edition
Volume52
Issue number23
DOIs
StatePublished - 3 Jun 2013
Externally publishedYes

Keywords

  • click chemistry
  • dark-field microscopy
  • nanoparticles
  • plasmon resonance scattering spectroscopy
  • reaction monitoring

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