Phosphine-catalyzed Friedel-Crafts reaction of naphthols with: Para -quinone methides: Expedient access to triarylmethanes

  • Tao Zhou
  • , Shenhuan Li
  • , Ben Huang
  • , Cao Li
  • , Yang Zhao
  • , Jieqiong Chen
  • , Aoling Chen
  • , Yuanjin Xiao
  • , Lu Liu*
  • , Junliang Zhang
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

58 Scopus citations

Abstract

We developed a novel phosphine-catalyzed Friedel-Crafts reaction of naphthols with para-quinone methides (p-QMs). This reaction provided a promising method for the synthesis of triarylmethanes, which widely exist in natural products and in molecules which have been shown to have biological and pharmacological activity.

Original languageEnglish
Pages (from-to)4941-4945
Number of pages5
JournalOrganic and Biomolecular Chemistry
Volume15
Issue number23
DOIs
StatePublished - 2017

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