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Pd(0)-catalyzed coupling-cyclization of 2-(2′,3′-Allenyl) acetylacetates and organic halides: An efficient synthesis of 4,5-dihydrofuran derivatives

  • Shengming Ma*
  • , Zilong Zheng
  • , Xuefeng Jiang
  • *Corresponding author for this work
  • CAS - Shanghai Institute of Organic Chemistry

Research output: Contribution to journalArticlepeer-review

Abstract

Highly chemo- and regioselective Pd(0)-catalyzed coupling-cyclization of 2-(2′,3′-allenyl)acetylacetates with organic halides using K 3PO4 as base in DMF efficiently afforded 4,5-dihydrofuran derivatives in moderate to excellent yields, with a selectivity of >97:3.

Original languageEnglish
Pages (from-to)529-531
Number of pages3
JournalOrganic Letters
Volume9
Issue number3
DOIs
StatePublished - 1 Feb 2007
Externally publishedYes

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