Palladium-catalyzed synthesis of fluoreones from bis(2-bromophenyl)methanols

Qian Gao, Senmiao Xu

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

A palladium-catalyzed synthesis method of fluorenones has been developed. A variety of bis(2-bromophenyl)methanols could undergo the reaction smoothly in the presence of Pd(OAc)2, affording a series of fluorenones in moderate to good yields (two steps). Mechanistic studies reveal that the reaction might be triggered by oxidation of alcohol followed by intramolecular reductive coupling.

Original languageEnglish
Pages (from-to)208-212
Number of pages5
JournalOrganic and Biomolecular Chemistry
Volume16
Issue number2
DOIs
StatePublished - 2018
Externally publishedYes

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