Palladium-Catalyzed Intermolecular Heck-Type Dearomative [4 + 2] Annulation of 2 H-Isoindole Derivatives with Internal Alkynes

Tengfei Yao; Fang Zhang; Junliang Zhang; Lu Liu

doi:10.1021/acs.orglett.0c01643

Palladium-Catalyzed Intermolecular Heck-Type Dearomative [4 + 2] Annulation of 2 H-Isoindole Derivatives with Internal Alkynes

Tengfei Yao
, Fang Zhang
, Junliang Zhang^*
, Lu Liu^*

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Here, an interesting palladium-catalyzed intermolecular Heck-type dearomative [4 + 2] annulation of 2H-isoindole derivatives with internal alkynes has been developed, affording diverse polycyclic pyrrolidine scaffolds in good yield. This reaction is a useful method for the transformation of 2H-isoindole.

Original language	English
Pages (from-to)	5063-5067
Number of pages	5
Journal	Organic Letters
Volume	22
Issue number	13
DOIs	https://doi.org/10.1021/acs.orglett.0c01643
State	Published - 2 Jul 2020

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title = "Palladium-Catalyzed Intermolecular Heck-Type Dearomative [4 + 2] Annulation of 2 H-Isoindole Derivatives with Internal Alkynes",

abstract = "Here, an interesting palladium-catalyzed intermolecular Heck-type dearomative [4 + 2] annulation of 2H-isoindole derivatives with internal alkynes has been developed, affording diverse polycyclic pyrrolidine scaffolds in good yield. This reaction is a useful method for the transformation of 2H-isoindole.",

author = "Tengfei Yao and Fang Zhang and Junliang Zhang and Lu Liu",

note = "Publisher Copyright: Copyright {\textcopyright} 2020 American Chemical Society.",

year = "2020",

month = jul,

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doi = "10.1021/acs.orglett.0c01643",

language = "英语",

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journal = "Organic Letters",

issn = "1523-7060",

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T1 - Palladium-Catalyzed Intermolecular Heck-Type Dearomative [4 + 2] Annulation of 2 H-Isoindole Derivatives with Internal Alkynes

AU - Yao, Tengfei

AU - Zhang, Fang

AU - Zhang, Junliang

AU - Liu, Lu

PY - 2020/7/2

Y1 - 2020/7/2

N2 - Here, an interesting palladium-catalyzed intermolecular Heck-type dearomative [4 + 2] annulation of 2H-isoindole derivatives with internal alkynes has been developed, affording diverse polycyclic pyrrolidine scaffolds in good yield. This reaction is a useful method for the transformation of 2H-isoindole.

AB - Here, an interesting palladium-catalyzed intermolecular Heck-type dearomative [4 + 2] annulation of 2H-isoindole derivatives with internal alkynes has been developed, affording diverse polycyclic pyrrolidine scaffolds in good yield. This reaction is a useful method for the transformation of 2H-isoindole.

UR - https://www.scopus.com/pages/publications/85087027416

U2 - 10.1021/acs.orglett.0c01643

DO - 10.1021/acs.orglett.0c01643

M3 - 文章

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AN - SCOPUS:85087027416

SN - 1523-7060

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EP - 5067

JO - Organic Letters

JF - Organic Letters

IS - 13

ER -

Palladium-Catalyzed Intermolecular Heck-Type Dearomative [4 + 2] Annulation of 2 H-Isoindole Derivatives with Internal Alkynes

Abstract

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