Oxazolonaphthalimides and their hydroperoxides: Photophysical and photobiological properties

Wei Yao, Xuhong Qian

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Novel oxazolonaphthalimide hydroperoxides 2 and 3 have been designed, synthesized and shown to be very efficient in photocleavage of DNA by the plazmid nicking assay. The absorption and fluorescence properties of these compounds and their relevant intermediates are discussed. An explanation for the higher DNA-cleavage efficiency of these oxazole-conjugated naphthalimide hydroperoxides than the nonsubstituted counterpart 1 is provided.

Original languageEnglish
Pages (from-to)43-47
Number of pages5
JournalDyes and Pigments
Volume48
Issue number1
DOIs
StatePublished - Jan 2001
Externally publishedYes

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