Abstract
Novel oxazolonaphthalimide hydroperoxides 2 and 3 have been designed, synthesized and shown to be very efficient in photocleavage of DNA by the plazmid nicking assay. The absorption and fluorescence properties of these compounds and their relevant intermediates are discussed. An explanation for the higher DNA-cleavage efficiency of these oxazole-conjugated naphthalimide hydroperoxides than the nonsubstituted counterpart 1 is provided.
| Original language | English |
|---|---|
| Pages (from-to) | 43-47 |
| Number of pages | 5 |
| Journal | Dyes and Pigments |
| Volume | 48 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2001 |
| Externally published | Yes |