Organocatalytic asymmetric synthesis of 3-difluoroalkyl 3-hydroxyoxindoles

Yun Lin Liu; Jian Zhou

doi:10.1039/c2cc17140f

Organocatalytic asymmetric synthesis of 3-difluoroalkyl 3-hydroxyoxindoles

Yun Lin Liu
, Jian Zhou^*

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

Research output: Contribution to journal › Article › peer-review

143 Scopus citations

Abstract

We report the first example of highly enantioselective organocatalytic synthesis of 3-difluoroalkyl substituted 3-hydroxyoxindoles. The total synthesis of the difluoro analogue of convolutamydine E was achieved by this method.

Original language	English
Pages (from-to)	1919-1921
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	13
DOIs	https://doi.org/10.1039/c2cc17140f
State	Published - 16 Jan 2012

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title = "Organocatalytic asymmetric synthesis of 3-difluoroalkyl 3-hydroxyoxindoles",

abstract = "We report the first example of highly enantioselective organocatalytic synthesis of 3-difluoroalkyl substituted 3-hydroxyoxindoles. The total synthesis of the difluoro analogue of convolutamydine E was achieved by this method.",

author = "Liu, \{Yun Lin\} and Jian Zhou",

year = "2012",

month = jan,

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doi = "10.1039/c2cc17140f",

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AU - Liu, Yun Lin

AU - Zhou, Jian

PY - 2012/1/16

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N2 - We report the first example of highly enantioselective organocatalytic synthesis of 3-difluoroalkyl substituted 3-hydroxyoxindoles. The total synthesis of the difluoro analogue of convolutamydine E was achieved by this method.

AB - We report the first example of highly enantioselective organocatalytic synthesis of 3-difluoroalkyl substituted 3-hydroxyoxindoles. The total synthesis of the difluoro analogue of convolutamydine E was achieved by this method.

UR - https://www.scopus.com/pages/publications/84862908105

U2 - 10.1039/c2cc17140f

DO - 10.1039/c2cc17140f

M3 - 文章

C2 - 22228324

AN - SCOPUS:84862908105

SN - 1359-7345

VL - 48

SP - 1919

EP - 1921

JO - Chemical Communications

JF - Chemical Communications

IS - 13

ER -

Organocatalytic asymmetric synthesis of 3-difluoroalkyl 3-hydroxyoxindoles

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