Organocatalytic asymmetric Strecker reaction of di- and trifluoromethyl ketoimines. Remarkable fluorine effect

Yun Lin Liu; Tao Da Shi; Feng Zhou; Xiao Li Zhao; Xin Wang; Jian Zhou

doi:10.1021/ol201316z

Organocatalytic asymmetric Strecker reaction of di- and trifluoromethyl ketoimines. Remarkable fluorine effect

Yun Lin Liu
, Tao Da Shi
, Feng Zhou
, Xiao Li Zhao
, Xin Wang^*
, Jian Zhou

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

Research output: Contribution to journal › Article › peer-review

181 Scopus citations

Abstract

A highly enantioselective Strecker reaction of difluoromethyl and trifluoromethyl ketoimines was developed. Remarkable fluorine effect on the reactivity and selectivity is observed and discussed.

Original language	English
Pages (from-to)	3826-3829
Number of pages	4
Journal	Organic Letters
Volume	13
Issue number	15
DOIs	https://doi.org/10.1021/ol201316z
State	Published - 5 Aug 2011

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10.1021/ol201316z

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@article{11799cd54c334090ae386a5d19bf5778,

title = "Organocatalytic asymmetric Strecker reaction of di- and trifluoromethyl ketoimines. Remarkable fluorine effect",

abstract = "A highly enantioselective Strecker reaction of difluoromethyl and trifluoromethyl ketoimines was developed. Remarkable fluorine effect on the reactivity and selectivity is observed and discussed.",

author = "Liu, \{Yun Lin\} and Shi, \{Tao Da\} and Feng Zhou and Zhao, \{Xiao Li\} and Xin Wang and Jian Zhou",

year = "2011",

month = aug,

day = "5",

doi = "10.1021/ol201316z",

language = "英语",

volume = "13",

pages = "3826--3829",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

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TY - JOUR

T1 - Organocatalytic asymmetric Strecker reaction of di- and trifluoromethyl ketoimines. Remarkable fluorine effect

AU - Liu, Yun Lin

AU - Shi, Tao Da

AU - Zhou, Feng

AU - Zhao, Xiao Li

AU - Wang, Xin

AU - Zhou, Jian

PY - 2011/8/5

Y1 - 2011/8/5

N2 - A highly enantioselective Strecker reaction of difluoromethyl and trifluoromethyl ketoimines was developed. Remarkable fluorine effect on the reactivity and selectivity is observed and discussed.

AB - A highly enantioselective Strecker reaction of difluoromethyl and trifluoromethyl ketoimines was developed. Remarkable fluorine effect on the reactivity and selectivity is observed and discussed.

UR - https://www.scopus.com/pages/publications/79961074469

U2 - 10.1021/ol201316z

DO - 10.1021/ol201316z

M3 - 文章

AN - SCOPUS:79961074469

SN - 1523-7060

VL - 13

SP - 3826

EP - 3829

JO - Organic Letters

JF - Organic Letters

IS - 15

ER -

Organocatalytic asymmetric Strecker reaction of di- and trifluoromethyl ketoimines. Remarkable fluorine effect

Abstract

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