Optical focusing through biological tissue and tissue-mimicking phantoms up to 9.6 centimeters thick with digital optical phase conjugation

  • Yuecheng Shen
  • , Yan Liu
  • , Cheng Ma
  • , Lihong V. Wang*
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Optical phase conjugation (OPC) based wavefront shaping techniques focus light through or within scattering media, which is critically important for deep-tissue optical imaging, manipulation, and therapy. However, to date, the sample thicknesses used in wavefront shaping experiments have been limited to only a few millimeters or several transport mean free paths. Here, by using a long-coherence-length laser and an optimized digital OPC system that efficiently delivers light power, we focused 532 nm light through tissue-mimicking phantoms up to 9.6 cm thick, as well as through ex vivo chicken breast tissue up to 2.5 cm thick.

Original languageEnglish
Title of host publicationAdaptive Optics and Wavefront Control for Biological Systems III
EditorsJoel Kubby, Thomas G. Bifano, Sylvain Gigan
PublisherSPIE
ISBN (Electronic)9781510605879
DOIs
StatePublished - 2017
Externally publishedYes
EventAdaptive Optics and Wavefront Control for Biological Systems III - San Francisco, United States
Duration: 28 Jan 201730 Jan 2017

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10073
ISSN (Print)1605-7422

Conference

ConferenceAdaptive Optics and Wavefront Control for Biological Systems III
Country/TerritoryUnited States
CitySan Francisco
Period28/01/1730/01/17

Keywords

  • Adaptive optics
  • Focusing light through scattering media
  • Holographic interferometry
  • Optical phase conjugation
  • Turbid media
  • Wavefront shaping

Fingerprint

Dive into the research topics of 'Optical focusing through biological tissue and tissue-mimicking phantoms up to 9.6 centimeters thick with digital optical phase conjugation'. Together they form a unique fingerprint.

Cite this