One-pot aqueous synthesis of gadolinium doped CdTe quantum dots with dual imaging modalities

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Abstract

A facile one-pot strategy has been developed for the aqueous synthesis of Gd doped CdTe (Gd:CdTe) QDs as fluorescence and magnetic resonance imaging dual-modal agent. The prepared Gd:CdTe QDs showed narrow size distribution and the average size was less than 5 nm. The amount of Gd3+ dopant in Gd:CdTe QDs significantly affected the optical properties of obtained QDs. The highest PL QY for the prepared Gd:CdTe QDs was up to 42.5%. The QDs showed the weak toxicity and significant enhancement in MRI signal. The specific relaxivity value (r1) was determined to be 4.22 mM-1s-1. These properties make the prepared Gd:CdTe QDs be an effective dual-modal imaging agent and have great potential applications in biomedical field.

Original languageEnglish
Pages (from-to)14-20
Number of pages7
JournalTalanta
Volume155
DOIs
StatePublished - 1 Aug 2016

Keywords

  • Aqueous synthesis
  • Fluorescence
  • Gd doped CdTe
  • MR imaging
  • Quantum dots

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