Nuclear receptors link gender dimorphism of renal disease progression

Y. Guan

doi:10.1038/sj.ki.5001961

Nuclear receptors link gender dimorphism of renal disease progression

Y. Guan^*

^*Corresponding author for this work

Research output: Contribution to journal › Comment/debate

3 Scopus citations

Abstract

Profound gender differences in the progression of chronic kidney disease (CKD) remain poorly understood. Differential expression of the genes for male- and female-specific proteins in the kidney has been proposed to account for this clinical phenomenon. Lu and colleagues provide evidence that the signaling pathways of the nuclear receptors ERα, AR and PPARα are associated with gender differences in CKD progression.

Original language	English
Pages (from-to)	1889-1890
Number of pages	2
Journal	Kidney International
Volume	70
Issue number	11
DOIs	https://doi.org/10.1038/sj.ki.5001961
State	Published - 2 Dec 2006
Externally published	Yes

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10.1038/sj.ki.5001961

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title = "Nuclear receptors link gender dimorphism of renal disease progression",

abstract = "Profound gender differences in the progression of chronic kidney disease (CKD) remain poorly understood. Differential expression of the genes for male- and female-specific proteins in the kidney has been proposed to account for this clinical phenomenon. Lu and colleagues provide evidence that the signaling pathways of the nuclear receptors ERα, AR and PPARα are associated with gender differences in CKD progression.",

author = "Y. Guan",

year = "2006",

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doi = "10.1038/sj.ki.5001961",

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AU - Guan, Y.

PY - 2006/12/2

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N2 - Profound gender differences in the progression of chronic kidney disease (CKD) remain poorly understood. Differential expression of the genes for male- and female-specific proteins in the kidney has been proposed to account for this clinical phenomenon. Lu and colleagues provide evidence that the signaling pathways of the nuclear receptors ERα, AR and PPARα are associated with gender differences in CKD progression.

AB - Profound gender differences in the progression of chronic kidney disease (CKD) remain poorly understood. Differential expression of the genes for male- and female-specific proteins in the kidney has been proposed to account for this clinical phenomenon. Lu and colleagues provide evidence that the signaling pathways of the nuclear receptors ERα, AR and PPARα are associated with gender differences in CKD progression.

UR - https://www.scopus.com/pages/publications/33845275161

U2 - 10.1038/sj.ki.5001961

DO - 10.1038/sj.ki.5001961

M3 - 评论/辩论

C2 - 17130819

AN - SCOPUS:33845275161

SN - 0085-2538

VL - 70

SP - 1889

EP - 1890

JO - Kidney International

JF - Kidney International

IS - 11

ER -

Nuclear receptors link gender dimorphism of renal disease progression

Abstract

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