NIR-triggered anticancer drug delivery by upconverting nanoparticles with integrated azobenzene-modified mesoporous silica

Jianan Liu; Wenbo Bu; Limin Pan; Jianlin Shi

doi:10.1002/anie.201300183

NIR-triggered anticancer drug delivery by upconverting nanoparticles with integrated azobenzene-modified mesoporous silica

Jianan Liu, Wenbo Bu, Limin Pan, Jianlin Shi

CAS - Shanghai Institute of Ceramics

Research output: Contribution to journal › Article › peer-review

716 Scopus citations

Abstract

Photomediated drug release: Silica-coated upconverting nanoparticles with mesopores modified by azobenzene molecules were synthesized. The azobenzene molecules make possible the release of the anticancer drug doxorubicin from the pore network of the mesoporous silica outer layer by irradiation with near-infrared (NIR) laser light. The release is regulated by the trans-cis photoisomerization of the azobenzene molecules (see picture).

Original language	English
Pages (from-to)	4375-4379
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	52
Issue number	16
DOIs	https://doi.org/10.1002/anie.201300183
State	Published - 15 Apr 2013
Externally published	Yes

Keywords

cancer
drug delivery
mesoporous materials
upconverting nanoparticles

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/anie.201300183

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title = "NIR-triggered anticancer drug delivery by upconverting nanoparticles with integrated azobenzene-modified mesoporous silica",

abstract = "Photomediated drug release: Silica-coated upconverting nanoparticles with mesopores modified by azobenzene molecules were synthesized. The azobenzene molecules make possible the release of the anticancer drug doxorubicin from the pore network of the mesoporous silica outer layer by irradiation with near-infrared (NIR) laser light. The release is regulated by the trans-cis photoisomerization of the azobenzene molecules (see picture).",

keywords = "cancer, drug delivery, mesoporous materials, upconverting nanoparticles",

author = "Jianan Liu and Wenbo Bu and Limin Pan and Jianlin Shi",

year = "2013",

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language = "英语",

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T1 - NIR-triggered anticancer drug delivery by upconverting nanoparticles with integrated azobenzene-modified mesoporous silica

AU - Liu, Jianan

AU - Bu, Wenbo

AU - Pan, Limin

AU - Shi, Jianlin

PY - 2013/4/15

Y1 - 2013/4/15

N2 - Photomediated drug release: Silica-coated upconverting nanoparticles with mesopores modified by azobenzene molecules were synthesized. The azobenzene molecules make possible the release of the anticancer drug doxorubicin from the pore network of the mesoporous silica outer layer by irradiation with near-infrared (NIR) laser light. The release is regulated by the trans-cis photoisomerization of the azobenzene molecules (see picture).

AB - Photomediated drug release: Silica-coated upconverting nanoparticles with mesopores modified by azobenzene molecules were synthesized. The azobenzene molecules make possible the release of the anticancer drug doxorubicin from the pore network of the mesoporous silica outer layer by irradiation with near-infrared (NIR) laser light. The release is regulated by the trans-cis photoisomerization of the azobenzene molecules (see picture).

KW - cancer

KW - drug delivery

KW - mesoporous materials

KW - upconverting nanoparticles

UR - https://www.scopus.com/pages/publications/84876257520

U2 - 10.1002/anie.201300183

DO - 10.1002/anie.201300183

M3 - 文章

C2 - 23495013

AN - SCOPUS:84876257520

SN - 1433-7851

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JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 16

ER -

NIR-triggered anticancer drug delivery by upconverting nanoparticles with integrated azobenzene-modified mesoporous silica

Abstract

Keywords

UN SDGs

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