Ni(ClO4)2-catalysed regio- and diastereoselective [3+2] cycloaddition of indoles and aryl oxiranyl-dicarboxylates/diketones: A facile access to furo[3,4-b]indoles

  • Jieming Zhang
  • , Zuliang Chen
  • , Hai Hong Wu*
  • , Junliang Zhang
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

70 Scopus citations

Abstract

Ni(ClO4)2·6H2O-catalysed regioselective and diastereoselective [3+2]-annulations of aryl oxiranyl-dicarboxylates and indoles via selective C–C bond cleavage of oxirane were revealed. The cycloadditions proceed smoothly with high regio- and diastereoselectivity under mild conditions leading to 1H-furo[3,4-b]indoles in good to excellent yields.

Original languageEnglish
Pages (from-to)1817-1819
Number of pages3
JournalChemical Communications
Volume48
Issue number12
DOIs
StatePublished - 12 Jan 2012

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