Nickel-catalyzed regio- And diastereoselective hydroarylative and hydroalkenylative cyclization of 1,6-dienes

Zhengshuai Xu; Yitian Tang; Chaoren Shen; Hongru Zhang; Yuxin Gan; Xiaolei Ji; Xinxin Tian; Kaiwu Dong

doi:10.1039/c9cc09450d

Nickel-catalyzed regio- And diastereoselective hydroarylative and hydroalkenylative cyclization of 1,6-dienes

Zhengshuai Xu
, Yitian Tang
, Chaoren Shen
, Hongru Zhang
, Yuxin Gan
, Xiaolei Ji
, Xinxin Tian
, Kaiwu Dong^*

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

An unprecedented nickel-catalyzed hydroarylative and hydroalkenylative cyclization of unsymmetrically substituted 1,6-dienes with organoboronic acid was developed by using MeOH as the hydrogen source and employing commercially available Ni(η2-1,5-cyclooctadiene)2 as the catalyst. A series of biologically interesting cyclic products were afforded in moderate to excellent yields with high regio- and diastereoselectivities.

Original language	English
Pages (from-to)	7741-7744
Number of pages	4
Journal	Chemical Communications
Volume	56
Issue number	56
DOIs	https://doi.org/10.1039/c9cc09450d
State	Published - 18 Jul 2020

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title = "Nickel-catalyzed regio- And diastereoselective hydroarylative and hydroalkenylative cyclization of 1,6-dienes",

abstract = "An unprecedented nickel-catalyzed hydroarylative and hydroalkenylative cyclization of unsymmetrically substituted 1,6-dienes with organoboronic acid was developed by using MeOH as the hydrogen source and employing commercially available Ni(η2-1,5-cyclooctadiene)2 as the catalyst. A series of biologically interesting cyclic products were afforded in moderate to excellent yields with high regio- and diastereoselectivities.",

author = "Zhengshuai Xu and Yitian Tang and Chaoren Shen and Hongru Zhang and Yuxin Gan and Xiaolei Ji and Xinxin Tian and Kaiwu Dong",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",

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doi = "10.1039/c9cc09450d",

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T1 - Nickel-catalyzed regio- And diastereoselective hydroarylative and hydroalkenylative cyclization of 1,6-dienes

AU - Xu, Zhengshuai

AU - Tang, Yitian

AU - Shen, Chaoren

AU - Zhang, Hongru

AU - Gan, Yuxin

AU - Ji, Xiaolei

AU - Tian, Xinxin

AU - Dong, Kaiwu

PY - 2020/7/18

Y1 - 2020/7/18

N2 - An unprecedented nickel-catalyzed hydroarylative and hydroalkenylative cyclization of unsymmetrically substituted 1,6-dienes with organoboronic acid was developed by using MeOH as the hydrogen source and employing commercially available Ni(η2-1,5-cyclooctadiene)2 as the catalyst. A series of biologically interesting cyclic products were afforded in moderate to excellent yields with high regio- and diastereoselectivities.

AB - An unprecedented nickel-catalyzed hydroarylative and hydroalkenylative cyclization of unsymmetrically substituted 1,6-dienes with organoboronic acid was developed by using MeOH as the hydrogen source and employing commercially available Ni(η2-1,5-cyclooctadiene)2 as the catalyst. A series of biologically interesting cyclic products were afforded in moderate to excellent yields with high regio- and diastereoselectivities.

UR - https://www.scopus.com/pages/publications/85088179738

U2 - 10.1039/c9cc09450d

DO - 10.1039/c9cc09450d

M3 - 文章

C2 - 32558829

AN - SCOPUS:85088179738

SN - 1359-7345

VL - 56

SP - 7741

EP - 7744

JO - Chemical Communications

JF - Chemical Communications

IS - 56

ER -

Nickel-catalyzed regio- And diastereoselective hydroarylative and hydroalkenylative cyclization of 1,6-dienes

Abstract

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