New domino approach for the synthesis of 2,3-disubstituted benzo[b]furans via copper-catalyzed multi-component coupling reactions followed by cyclization

  • Hongfeng Li
  • , Jun Liu
  • , Bin Yan
  • , Yanzhong Li*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

64 Scopus citations

Abstract

An efficient domino process for the construction of 2,3-disubstituted benzo[b]furans has been developed via copper-catalyzed three-component coupling reactions of salicylaldehydes, amines, and alkynes followed by base-assisted O-annulation reaction.

Original languageEnglish
Pages (from-to)2353-2357
Number of pages5
JournalTetrahedron Letters
Volume50
Issue number20
DOIs
StatePublished - 20 May 2009

Keywords

  • Benzo[b]furan
  • Copper catalysis
  • Domino reaction
  • Three-component coupling

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