New domino approach for the synthesis of 2,3-disubstituted benzo[b]furans via copper-catalyzed multi-component coupling reactions followed by cyclization

Hongfeng Li; Jun Liu; Bin Yan; Yanzhong Li

doi:10.1016/j.tetlet.2009.02.204

New domino approach for the synthesis of 2,3-disubstituted benzo[b]furans via copper-catalyzed multi-component coupling reactions followed by cyclization

Hongfeng Li
, Jun Liu
, Bin Yan
, Yanzhong Li^*

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University
CAS - Shanghai Institute of Organic Chemistry

Research output: Contribution to journal › Article › peer-review

65 Scopus citations

Abstract

An efficient domino process for the construction of 2,3-disubstituted benzo[b]furans has been developed via copper-catalyzed three-component coupling reactions of salicylaldehydes, amines, and alkynes followed by base-assisted O-annulation reaction.

Original language	English
Pages (from-to)	2353-2357
Number of pages	5
Journal	Tetrahedron Letters
Volume	50
Issue number	20
DOIs	https://doi.org/10.1016/j.tetlet.2009.02.204
State	Published - 20 May 2009

Keywords

Benzo[b]furan
Copper catalysis
Domino reaction
Three-component coupling

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10.1016/j.tetlet.2009.02.204

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title = "New domino approach for the synthesis of 2,3-disubstituted benzo[b]furans via copper-catalyzed multi-component coupling reactions followed by cyclization",

abstract = "An efficient domino process for the construction of 2,3-disubstituted benzo[b]furans has been developed via copper-catalyzed three-component coupling reactions of salicylaldehydes, amines, and alkynes followed by base-assisted O-annulation reaction.",

keywords = "Benzo[b]furan, Copper catalysis, Domino reaction, Three-component coupling",

author = "Hongfeng Li and Jun Liu and Bin Yan and Yanzhong Li",

year = "2009",

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doi = "10.1016/j.tetlet.2009.02.204",

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AU - Li, Hongfeng

AU - Liu, Jun

AU - Yan, Bin

AU - Li, Yanzhong

PY - 2009/5/20

Y1 - 2009/5/20

N2 - An efficient domino process for the construction of 2,3-disubstituted benzo[b]furans has been developed via copper-catalyzed three-component coupling reactions of salicylaldehydes, amines, and alkynes followed by base-assisted O-annulation reaction.

AB - An efficient domino process for the construction of 2,3-disubstituted benzo[b]furans has been developed via copper-catalyzed three-component coupling reactions of salicylaldehydes, amines, and alkynes followed by base-assisted O-annulation reaction.

KW - Benzo[b]furan

KW - Copper catalysis

KW - Domino reaction

KW - Three-component coupling

UR - https://www.scopus.com/pages/publications/63349101717

U2 - 10.1016/j.tetlet.2009.02.204

DO - 10.1016/j.tetlet.2009.02.204

M3 - 文章

AN - SCOPUS:63349101717

SN - 0040-4039

VL - 50

SP - 2353

EP - 2357

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 20

ER -

New domino approach for the synthesis of 2,3-disubstituted benzo[b]furans via copper-catalyzed multi-component coupling reactions followed by cyclization

Abstract

Keywords

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