Neojaponicone A, a bioactive sesquiterpene lactone dimer with an unprecedented carbon skeleton from Inula japonica

Jiang Jiang Qin; Li Yan Wang; Jia Xian Zhu; Hui Zi Jin; Jian Jun Fu; Xiao Feng Liu; Hong Lin Li; Wei Dong Zhang

doi:10.1039/c0cc03572f

Neojaponicone A, a bioactive sesquiterpene lactone dimer with an unprecedented carbon skeleton from Inula japonica

Jiang Jiang Qin
, Li Yan Wang
, Jia Xian Zhu
, Hui Zi Jin^*
, Jian Jun Fu
, Xiao Feng Liu
, Hong Lin Li
, Wei Dong Zhang

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Abstract

Five new dimeric sesquiterpene lactones, neojaponicone A (1) and japonicones M-P (2-5) were isolated from the aerial part of Inula japonica. Neojaponicone A (1) has an unprecedented carbon skeleton with an unusual valerolactone system formed between a guaianolide and an eudesmane. The structure and absolute configuration of 1 were established by extensive analysis of spectroscopic data and computational approaches.

Original language	English
Pages (from-to)	1222-1224
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	4
DOIs	https://doi.org/10.1039/c0cc03572f
State	Published - 10 Jan 2011
Externally published	Yes

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title = "Neojaponicone A, a bioactive sesquiterpene lactone dimer with an unprecedented carbon skeleton from Inula japonica",

abstract = "Five new dimeric sesquiterpene lactones, neojaponicone A (1) and japonicones M-P (2-5) were isolated from the aerial part of Inula japonica. Neojaponicone A (1) has an unprecedented carbon skeleton with an unusual valerolactone system formed between a guaianolide and an eudesmane. The structure and absolute configuration of 1 were established by extensive analysis of spectroscopic data and computational approaches.",

author = "Qin, \{Jiang Jiang\} and Wang, \{Li Yan\} and Zhu, \{Jia Xian\} and Jin, \{Hui Zi\} and Fu, \{Jian Jun\} and Liu, \{Xiao Feng\} and Li, \{Hong Lin\} and Zhang, \{Wei Dong\}",

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doi = "10.1039/c0cc03572f",

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T1 - Neojaponicone A, a bioactive sesquiterpene lactone dimer with an unprecedented carbon skeleton from Inula japonica

AU - Qin, Jiang Jiang

AU - Wang, Li Yan

AU - Zhu, Jia Xian

AU - Jin, Hui Zi

AU - Fu, Jian Jun

AU - Liu, Xiao Feng

AU - Li, Hong Lin

AU - Zhang, Wei Dong

PY - 2011/1/10

Y1 - 2011/1/10

N2 - Five new dimeric sesquiterpene lactones, neojaponicone A (1) and japonicones M-P (2-5) were isolated from the aerial part of Inula japonica. Neojaponicone A (1) has an unprecedented carbon skeleton with an unusual valerolactone system formed between a guaianolide and an eudesmane. The structure and absolute configuration of 1 were established by extensive analysis of spectroscopic data and computational approaches.

AB - Five new dimeric sesquiterpene lactones, neojaponicone A (1) and japonicones M-P (2-5) were isolated from the aerial part of Inula japonica. Neojaponicone A (1) has an unprecedented carbon skeleton with an unusual valerolactone system formed between a guaianolide and an eudesmane. The structure and absolute configuration of 1 were established by extensive analysis of spectroscopic data and computational approaches.

UR - https://www.scopus.com/pages/publications/78651274028

U2 - 10.1039/c0cc03572f

DO - 10.1039/c0cc03572f

M3 - 文章

C2 - 21103596

AN - SCOPUS:78651274028

SN - 1359-7345

VL - 47

SP - 1222

EP - 1224

JO - Chemical Communications

JF - Chemical Communications

IS - 4

ER -

Neojaponicone A, a bioactive sesquiterpene lactone dimer with an unprecedented carbon skeleton from Inula japonica

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