N′-tert-butyl-N′-aroyl-N-(alkoxycarbonylmethyl)-N- aroylhydrazines, a novel nonsteroidal ecdysone agonist: Syntheses, insecticidal activity, conformational, and crystal structure analysis

Seventeen N′-tert-butyl-N′-aroyl-N-(alkoxycarbonylmethyl)-N-aroylhydrazines were synthesized, and their insecticidal activities against armyworm (Leucania separata (Walker)) were tested. The conformation and structure of compound 1b was studied by ¹H NMR spectroscopy and X-ray crystallography. The crystal structure belongs to the orthorhombic system and the N-N bond adopts a gauche conformation, which was assumed to be the active conformation, with a dihedral angle of 69.9°.