Multiple functionalized carbon quantum dots for targeting glioma and tissue imaging

Lipeng Gao; Xiao Zhao; Jing Wang; Yiting Wang; Lei Yu; Hui Peng; Jianzhong Zhu

doi:10.1016/j.optmat.2017.11.044

Multiple functionalized carbon quantum dots for targeting glioma and tissue imaging

Lipeng Gao, Xiao Zhao, Jing Wang, Yiting Wang, Lei Yu, Hui Peng, Jianzhong Zhu

School of Physics and Electronic Science

East China Normal University

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

Carbon quantum dots (CQDs) was successfully functionalized with Mal-PEG-NHS linked RGERPPR. They exhibit double functions of both tissue imaging and targeting to brain gliomas. The mean size of the functionalized CQDs about 9.0 ± 2.0 nm. The maximum absorption wavelength of the functionalized CQDs appear at 230 nm. The peak of the fluorescence spectra for the functionalized CQDs is at 460 nm, red shifted by 20 nm comparing with the unmodified CQDs. This may be due to the increased particle size. The functionalized CQDs were successfully applied to imaging and targeting gliomas.

Original language	English
Pages (from-to)	764-769
Number of pages	6
Journal	Optical Materials
Volume	75
DOIs	https://doi.org/10.1016/j.optmat.2017.11.044
State	Published - Jan 2018

Keywords

Blood brain barrier
Carbon quantum dots
Glioma targeting
Mal-PEG-NHS
RGERPPR
Tissue imaging

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10.1016/j.optmat.2017.11.044

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title = "Multiple functionalized carbon quantum dots for targeting glioma and tissue imaging",

abstract = "Carbon quantum dots (CQDs) was successfully functionalized with Mal-PEG-NHS linked RGERPPR. They exhibit double functions of both tissue imaging and targeting to brain gliomas. The mean size of the functionalized CQDs about 9.0 ± 2.0 nm. The maximum absorption wavelength of the functionalized CQDs appear at 230 nm. The peak of the fluorescence spectra for the functionalized CQDs is at 460 nm, red shifted by 20 nm comparing with the unmodified CQDs. This may be due to the increased particle size. The functionalized CQDs were successfully applied to imaging and targeting gliomas.",

keywords = "Blood brain barrier, Carbon quantum dots, Glioma targeting, Mal-PEG-NHS, RGERPPR, Tissue imaging",

author = "Lipeng Gao and Xiao Zhao and Jing Wang and Yiting Wang and Lei Yu and Hui Peng and Jianzhong Zhu",

note = "Publisher Copyright: {\textcopyright} 2017",

year = "2018",

month = jan,

doi = "10.1016/j.optmat.2017.11.044",

language = "英语",

volume = "75",

pages = "764--769",

journal = "Optical Materials",

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TY - JOUR

T1 - Multiple functionalized carbon quantum dots for targeting glioma and tissue imaging

AU - Gao, Lipeng

AU - Zhao, Xiao

AU - Wang, Jing

AU - Wang, Yiting

AU - Yu, Lei

AU - Peng, Hui

AU - Zhu, Jianzhong

PY - 2018/1

Y1 - 2018/1

N2 - Carbon quantum dots (CQDs) was successfully functionalized with Mal-PEG-NHS linked RGERPPR. They exhibit double functions of both tissue imaging and targeting to brain gliomas. The mean size of the functionalized CQDs about 9.0 ± 2.0 nm. The maximum absorption wavelength of the functionalized CQDs appear at 230 nm. The peak of the fluorescence spectra for the functionalized CQDs is at 460 nm, red shifted by 20 nm comparing with the unmodified CQDs. This may be due to the increased particle size. The functionalized CQDs were successfully applied to imaging and targeting gliomas.

AB - Carbon quantum dots (CQDs) was successfully functionalized with Mal-PEG-NHS linked RGERPPR. They exhibit double functions of both tissue imaging and targeting to brain gliomas. The mean size of the functionalized CQDs about 9.0 ± 2.0 nm. The maximum absorption wavelength of the functionalized CQDs appear at 230 nm. The peak of the fluorescence spectra for the functionalized CQDs is at 460 nm, red shifted by 20 nm comparing with the unmodified CQDs. This may be due to the increased particle size. The functionalized CQDs were successfully applied to imaging and targeting gliomas.

KW - Blood brain barrier

KW - Carbon quantum dots

KW - Glioma targeting

KW - Mal-PEG-NHS

KW - RGERPPR

KW - Tissue imaging

UR - https://www.scopus.com/pages/publications/85036463268

U2 - 10.1016/j.optmat.2017.11.044

DO - 10.1016/j.optmat.2017.11.044

M3 - 文章

AN - SCOPUS:85036463268

SN - 0925-3467

VL - 75

SP - 764

EP - 769

JO - Optical Materials

JF - Optical Materials

ER -

Multiple functionalized carbon quantum dots for targeting glioma and tissue imaging

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Keywords

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