Multifunctional mesoporous composite nanocapsules for highly efficient MRI-guided high-intensity focused ultrasound cancer surgery

Yu Chen, Hangrong Chen, Yang Sun, Yuanyi Zheng, Deping Zeng, Faqi Li, Shengjian Zhang, Xia Wang, Kun Zhang, Ming Ma, Qianjun He, Linlin Zhang, Jianlin Shi

Research output: Contribution to journalArticlepeer-review

179 Scopus citations

Abstract

Bloodless surgical knife: Nano-biotechnology has been introduced into imaging-guided high-intensity focused ultrasound (HIFU) cancer surgery by adopting engineered multifunctional manganese-based mesoporous composite nanocapsules as the contrast agents for T 1-weighted magnetic resonance imaging (MRI) and simultaneously as synergistic agents for MRI-guided HIFU cancer surgery.

Original languageEnglish
Pages (from-to)12505-12509
Number of pages5
JournalAngewandte Chemie - International Edition
Volume50
Issue number52
DOIs
StatePublished - 23 Dec 2011
Externally publishedYes

Keywords

  • high-intensity focused ultrasound
  • imaging agents
  • magnetic resonance imaging
  • mesoporous materials
  • nanotechnology

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