Morphology-Tailoring of a Red AIEgen from Microsized Rods to Nanospheres for Tumor-Targeted Bioimaging

Yongsheng Li; Andong Shao; Yao Wang; Ju Mei; Dechao Niu; Jinlou Gu; Ping Shi; Weihong Zhu; He Tian; Jianlin Shi

doi:10.1002/adma.201504782

Morphology-Tailoring of a Red AIEgen from Microsized Rods to Nanospheres for Tumor-Targeted Bioimaging

Yongsheng Li^*
, Andong Shao
, Yao Wang
, Ju Mei
, Dechao Niu
, Jinlou Gu
, Ping Shi
, Weihong Zhu
, He Tian
, Jianlin Shi

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

97 Scopus citations

Abstract

Efficient morphology modulation of a red AIEgen from pristine microsized rods to nanospheres is achieved via encapsula ting QM-2 (quinolinemalononitrile-2) into hybrid micelles. This novel reagent shows great potential in tumor-targeted bioimaging because of its monodispersion in aqueous systems, the uniform diameter of ≈30 nm, enhanced fluorescence brightness with a large Stokes shift of 190 nm, and strongly increased biocompatibility and photostability.

Original language	English
Pages (from-to)	3187-3193
Number of pages	7
Journal	Advanced Materials
Volume	28
Issue number	16
DOIs	https://doi.org/10.1002/adma.201504782
State	Published - 27 Apr 2016
Externally published	Yes

Keywords

bioimaging
modulation
morphology
photostability
tumor targeting

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title = "Morphology-Tailoring of a Red AIEgen from Microsized Rods to Nanospheres for Tumor-Targeted Bioimaging",

abstract = "Efficient morphology modulation of a red AIEgen from pristine microsized rods to nanospheres is achieved via encapsula ting QM-2 (quinolinemalononitrile-2) into hybrid micelles. This novel reagent shows great potential in tumor-targeted bioimaging because of its monodispersion in aqueous systems, the uniform diameter of ≈30 nm, enhanced fluorescence brightness with a large Stokes shift of 190 nm, and strongly increased biocompatibility and photostability.",

keywords = "bioimaging, modulation, morphology, photostability, tumor targeting",

author = "Yongsheng Li and Andong Shao and Yao Wang and Ju Mei and Dechao Niu and Jinlou Gu and Ping Shi and Weihong Zhu and He Tian and Jianlin Shi",

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doi = "10.1002/adma.201504782",

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AU - Li, Yongsheng

AU - Shao, Andong

AU - Wang, Yao

AU - Mei, Ju

AU - Niu, Dechao

AU - Gu, Jinlou

AU - Shi, Ping

AU - Zhu, Weihong

AU - Tian, He

AU - Shi, Jianlin

PY - 2016/4/27

Y1 - 2016/4/27

N2 - Efficient morphology modulation of a red AIEgen from pristine microsized rods to nanospheres is achieved via encapsula ting QM-2 (quinolinemalononitrile-2) into hybrid micelles. This novel reagent shows great potential in tumor-targeted bioimaging because of its monodispersion in aqueous systems, the uniform diameter of ≈30 nm, enhanced fluorescence brightness with a large Stokes shift of 190 nm, and strongly increased biocompatibility and photostability.

AB - Efficient morphology modulation of a red AIEgen from pristine microsized rods to nanospheres is achieved via encapsula ting QM-2 (quinolinemalononitrile-2) into hybrid micelles. This novel reagent shows great potential in tumor-targeted bioimaging because of its monodispersion in aqueous systems, the uniform diameter of ≈30 nm, enhanced fluorescence brightness with a large Stokes shift of 190 nm, and strongly increased biocompatibility and photostability.

KW - bioimaging

KW - modulation

KW - morphology

KW - photostability

KW - tumor targeting

UR - https://www.scopus.com/pages/publications/84959441261

U2 - 10.1002/adma.201504782

DO - 10.1002/adma.201504782

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AN - SCOPUS:84959441261

SN - 0935-9648

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JO - Advanced Materials

JF - Advanced Materials

IS - 16

ER -

Morphology-Tailoring of a Red AIEgen from Microsized Rods to Nanospheres for Tumor-Targeted Bioimaging

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Keywords

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