TY - JOUR
T1 - Mild and efficient synthesis of N1,N5,N 10-tri-tert-butoxycarbonyl spermine
AU - Feng, Xiangjun
AU - Xia, Wenpin
AU - Luo, Yu
AU - Lu, Wei
PY - 2012/1
Y1 - 2012/1
N2 - This article describes a mild and efficient synthesis of N 1,N5,N10-tri-tert-butoxycarbonyl spermine from putrescine, with a 41% overall yield. The key steps include a Michael addition and Raney nickel (W-2) reduction. The advantages of this synthesis include a simple procedure, mild conditions, and good yields.
AB - This article describes a mild and efficient synthesis of N 1,N5,N10-tri-tert-butoxycarbonyl spermine from putrescine, with a 41% overall yield. The key steps include a Michael addition and Raney nickel (W-2) reduction. The advantages of this synthesis include a simple procedure, mild conditions, and good yields.
KW - Michael addition
KW - N ,N,N-tri-Boc spermine
KW - Raney nickel (W-2) reduction
KW - synthesis
UR - https://www.scopus.com/pages/publications/80052882683
U2 - 10.1080/00397911.2010.523856
DO - 10.1080/00397911.2010.523856
M3 - 文章
AN - SCOPUS:80052882683
SN - 0039-7911
VL - 42
SP - 274
EP - 278
JO - Synthetic Communications
JF - Synthetic Communications
IS - 2
ER -