Metal-Organic Frameworks with Boronic Acid Suspended and Their Implication for cis-Diol Moieties Binding

  • Xiangyang Zhu
  • , Jinlou Gu*
  • , Junying Zhu
  • , Yongsheng Li
  • , Liming Zhao
  • , Jianlin Shi
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

71 Scopus citations

Abstract

Introduction of accessible boronic acid functionality into metal-organic frameworks (MOFs) might to endow them with desired properties for potential applications in recognition and isolation of cis-diol containing biomolecules (CDBs). However, no investigation is found to address this topic until now. Herein, Cr-based MOFs of MIL-100 (MIL stands for Materials from Institut Lavoisier) integrated with different pendent boronic acid group (MIL-100-B) are reported. This new functional material is successfully prepared using a simple metal-ligand-fragment coassembly (MLFC) strategy with isostructure to the parent MIL-100 as verified by X-ray diffraction characterization. The integration and content tunability of the boronic acid group in the framework are confirmed by X-ray photoelectron spectroscopy and 11B NMR. Transmission electron microscopy reveals that MIL-100-B can evolve into well-defined morphology and nanoscale size at optimized boronic acid incorporating level. The obtained MOFs exhibit comparable surface areas and pore volumes with parent MIL-100 and present exceptional chemical stability in a wide pH range. The inherent boronic acid components in MIL-100-B can effectively serve as the recognition units for the cis-diol moieties and consequently enhance the capture capabilities for CDBs. The exceptional chemical stability, high porosity, and good reusability as well as the intrinsic cis-diol moieties recognition function prefigure great potential of the current MIL-100-B in CDBs purification, sensing, and separation applications. Introduction of accessible boronic acid functionality into metal-organic frameworks is successfully achieved using a facile linker fragmentation strategy. In virtue of their accessible boronic acid groups, exceptional chemical stability, as well as high porosity, the newly elaborated functional material offers a new platform for the recognition and separation of cis-diol containing biomolecules.

Original languageEnglish
Pages (from-to)3847-3854
Number of pages8
JournalAdvanced Functional Materials
Volume25
Issue number25
DOIs
StatePublished - 1 Jul 2015
Externally publishedYes

Keywords

  • boronic acid functionality
  • cis-diol moieties
  • linker fragmentation
  • metal-organic frameworks
  • reversible binding

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