Metabolic pathway for degradation of anthracene by halophilic Martelella sp. AD-3

Changzheng Cui, Lei Ma, Jie Shi, Kuangfei Lin, Qishi Luo, Yongdi Liu

Research output: Contribution to journalArticlepeer-review

40 Scopus citations

Abstract

Anthracene (40mgl-1) was completely depleted by Martelella sp. strain AD-3 under 3% salinity and a pH of 9.0 after 6 days of incubation. The metabolites were extracted and identified by high-performance liquid chromatography (HPLC) retention times, mass spectrometry, 1H and 13C nuclear magnetic resonance spectrometry, and comparison to authentic compounds or literature data. On the basis of the identified metabolites, enzyme activities and the utilization of probable intermediates, anthracene degradation by strain AD-3 is proposed via two distinct routes. In route I, metabolism of anthracene is initiated by the dioxygenation at C-1,2, then proceeds through 6,7-benzocoumarin, 3-hydroxy-2-naphthoic acid, salicylic acid and gentisic acid. In route II, anthracene is metabolized to 9,10-anthraquinone. The results suggest that strain AD-3 possesses efficient anthracene biodegradability in high salinity. To our knowledge, this work presents the first report of anthracene degradation by a halophilic PAH-degrading strain via two routes. The strain AD-3 may be a useful candidate for PAH-contaminated saline-alkali soil bioremediation.

Original languageEnglish
Pages (from-to)67-73
Number of pages7
JournalInternational Biodeterioration and Biodegradation
Volume89
DOIs
StatePublished - Apr 2014
Externally publishedYes

Keywords

  • 3-Hydroxy-2-naphthoic acid
  • Anthracene
  • Biodegradation
  • Metabolic pathway
  • Moderate halophilic bacteria

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