Merging base-promoted C-C bond cleavage and iron-catalyzed skeletal rearrangement involving C-C/C-H bond activation: Synthesis of highly functionalized carbazoles

Lingkai Kong; Mengdan Wang; Ye Wang; Bo Song; Yajie Yang; Qiyi Yao; Yanzhong Li

doi:10.1039/c8cc06074f

Merging base-promoted C-C bond cleavage and iron-catalyzed skeletal rearrangement involving C-C/C-H bond activation: Synthesis of highly functionalized carbazoles

Lingkai Kong, Mengdan Wang, Ye Wang, Bo Song, Yajie Yang, Qiyi Yao, Yanzhong Li

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

An efficient and atom-economical methodology for the synthesis of multi-substituted carbazoles starting from α-aryl ketones and ynones under mild reaction conditions has been developed. This process goes through Cs₂CO₃ promoted C-C σ-bond activation of α-aryl ketones followed by highly selective C-H bond activations and C-C bond fragmentations in a one-pot operation.

Original language	English
Pages (from-to)	11009-11012
Number of pages	4
Journal	Chemical Communications
Volume	54
Issue number	78
DOIs	https://doi.org/10.1039/c8cc06074f
State	Published - 2018

Access to Document

10.1039/c8cc06074f

Cite this

@article{b9b04e5047614f03a2e5f26ca3ab27b3,

title = "Merging base-promoted C-C bond cleavage and iron-catalyzed skeletal rearrangement involving C-C/C-H bond activation: Synthesis of highly functionalized carbazoles",

abstract = "An efficient and atom-economical methodology for the synthesis of multi-substituted carbazoles starting from α-aryl ketones and ynones under mild reaction conditions has been developed. This process goes through Cs2CO3 promoted C-C σ-bond activation of α-aryl ketones followed by highly selective C-H bond activations and C-C bond fragmentations in a one-pot operation.",

author = "Lingkai Kong and Mengdan Wang and Ye Wang and Bo Song and Yajie Yang and Qiyi Yao and Yanzhong Li",

note = "Publisher Copyright: {\textcopyright} 2018 The Royal Society of Chemistry.",

year = "2018",

doi = "10.1039/c8cc06074f",

language = "英语",

volume = "54",

pages = "11009--11012",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "78",

}

TY - JOUR

T1 - Merging base-promoted C-C bond cleavage and iron-catalyzed skeletal rearrangement involving C-C/C-H bond activation

T2 - Synthesis of highly functionalized carbazoles

AU - Kong, Lingkai

AU - Wang, Mengdan

AU - Wang, Ye

AU - Song, Bo

AU - Yang, Yajie

AU - Yao, Qiyi

AU - Li, Yanzhong

PY - 2018

Y1 - 2018

N2 - An efficient and atom-economical methodology for the synthesis of multi-substituted carbazoles starting from α-aryl ketones and ynones under mild reaction conditions has been developed. This process goes through Cs2CO3 promoted C-C σ-bond activation of α-aryl ketones followed by highly selective C-H bond activations and C-C bond fragmentations in a one-pot operation.

AB - An efficient and atom-economical methodology for the synthesis of multi-substituted carbazoles starting from α-aryl ketones and ynones under mild reaction conditions has been developed. This process goes through Cs2CO3 promoted C-C σ-bond activation of α-aryl ketones followed by highly selective C-H bond activations and C-C bond fragmentations in a one-pot operation.

UR - https://www.scopus.com/pages/publications/85054125018

U2 - 10.1039/c8cc06074f

DO - 10.1039/c8cc06074f

M3 - 文章

C2 - 30215063

AN - SCOPUS:85054125018

SN - 1359-7345

VL - 54

SP - 11009

EP - 11012

JO - Chemical Communications

JF - Chemical Communications

IS - 78

ER -

Merging base-promoted C-C bond cleavage and iron-catalyzed skeletal rearrangement involving C-C/C-H bond activation: Synthesis of highly functionalized carbazoles

Abstract

Access to Document

Other files and links

Fingerprint

Cite this