Abstract
Purpose: To analyze the expression pattern of Mef2c during zebrafish embryogenesis. Methods: We collected all the phases of zebrafish embryos to detect the expression pattern of Mef2c in the somite and the heart during zebrafish embryogenesis by whole mount in situ hybridization. Results: We first detected Mef2c expression at 13 hours post-fertilization in the somite that is the latest expression in the somite of Mef2c family. Expression of Mef2c in heart was detected as early as in somite and continued for 48 hours post-fertilization. Conclusions: We made clear the expression pattern of Mef2c during zebrafish embryogenesis in order to make sure that Mef2c plays important roles in the regulation of cardiac and skeletal muscle development.
| Original language | English |
|---|---|
| Pages (from-to) | 89-91 |
| Number of pages | 3 |
| Journal | Fudan University Journal of Medical Sciences |
| Volume | 33 |
| Issue number | 1 |
| State | Published - Jan 2006 |
| Externally published | Yes |
Keywords
- Mef2c
- RNA antisense probe
- Whole mount in situ hybridization
- Zebrafish