Mechanistic insight to the reaction pathway of aerobic oxidative C-C bond cleavage of α-hydroxy ketones

Hui Liu; Xuefeng Jiang

doi:10.1055/s-0033-1338421

Mechanistic insight to the reaction pathway of aerobic oxidative C-C bond cleavage of α-hydroxy ketones

Hui Liu, Xuefeng Jiang

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

A novel transition-metal-free aerobic oxidative C-C bond-cleavage method has been developed. Oxygen, the ideal oxidant, was used as the oxidizing reagent. The dimeric intermediate and ¹⁸O-isotopic-labeling control experiments partially disclosed the reaction mechanism.

Original language	English
Article number	ST-2013-P0170-SP
Pages (from-to)	1311-1315
Number of pages	5
Journal	Synlett
Volume	24
Issue number	11
DOIs	https://doi.org/10.1055/s-0033-1338421
State	Published - 2013

Keywords

C-C bond cleavage
aerobic oxidation
esterification
transition-metal-free
α-hydroxy ketones

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title = "Mechanistic insight to the reaction pathway of aerobic oxidative C-C bond cleavage of α-hydroxy ketones",

abstract = "A novel transition-metal-free aerobic oxidative C-C bond-cleavage method has been developed. Oxygen, the ideal oxidant, was used as the oxidizing reagent. The dimeric intermediate and 18O-isotopic-labeling control experiments partially disclosed the reaction mechanism.",

keywords = "C-C bond cleavage, aerobic oxidation, esterification, transition-metal-free, α-hydroxy ketones",

author = "Hui Liu and Xuefeng Jiang",

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AU - Liu, Hui

AU - Jiang, Xuefeng

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AB - A novel transition-metal-free aerobic oxidative C-C bond-cleavage method has been developed. Oxygen, the ideal oxidant, was used as the oxidizing reagent. The dimeric intermediate and 18O-isotopic-labeling control experiments partially disclosed the reaction mechanism.

KW - C-C bond cleavage

KW - aerobic oxidation

KW - esterification

KW - transition-metal-free

KW - α-hydroxy ketones

UR - https://www.scopus.com/pages/publications/84876403116

U2 - 10.1055/s-0033-1338421

DO - 10.1055/s-0033-1338421

M3 - 文章

AN - SCOPUS:84876403116

SN - 0936-5214

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JO - Synlett

JF - Synlett

IS - 11

M1 - ST-2013-P0170-SP

ER -

Mechanistic insight to the reaction pathway of aerobic oxidative C-C bond cleavage of α-hydroxy ketones

Abstract

Keywords

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