MALDI in-source photooxidation reactions for online peptide tagging

Liang Qiao; Christophe Roussel; Jingjing Wan; Jilie Kong; Pengyuan Yang; Hubert H. Girault; Baohong Liu

doi:10.1002/anie.200703876

MALDI in-source photooxidation reactions for online peptide tagging

Liang Qiao^*
, Christophe Roussel
, Jingjing Wan
, Jilie Kong
, Pengyuan Yang
, Hubert H. Girault
, Baohong Liu

^*Corresponding author for this work

Fudan University
Swiss Federal Institute of Technology Lausanne

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

(Chemical Equation Presented) A TiO₂ photoelectrode array has been designed to achieve efficient photoelectrochemical redox reactions with electron donors or acceptors during the laser desorption ionization process. By adding hydroquinone to a peptide mixture, the photoelectrochemically generated benzoquinone reacts with the cysteine residues to selectively form tagged cysteine-containing peptides, thus demonstrating that in-source oxidation reactions can be efficiently performed.

Original language	English
Pages (from-to)	2646-2648
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	47
Issue number	14
DOIs	https://doi.org/10.1002/anie.200703876
State	Published - 25 Mar 2008
Externally published	Yes

Keywords

Mass spectrometry
Peptides
Photoelectrodes
Photooxidation
Titanium dioxide

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10.1002/anie.200703876

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title = "MALDI in-source photooxidation reactions for online peptide tagging",

abstract = "(Chemical Equation Presented) A TiO2 photoelectrode array has been designed to achieve efficient photoelectrochemical redox reactions with electron donors or acceptors during the laser desorption ionization process. By adding hydroquinone to a peptide mixture, the photoelectrochemically generated benzoquinone reacts with the cysteine residues to selectively form tagged cysteine-containing peptides, thus demonstrating that in-source oxidation reactions can be efficiently performed.",

keywords = "Mass spectrometry, Peptides, Photoelectrodes, Photooxidation, Titanium dioxide",

author = "Liang Qiao and Christophe Roussel and Jingjing Wan and Jilie Kong and Pengyuan Yang and Girault, \{Hubert H.\} and Baohong Liu",

year = "2008",

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day = "25",

doi = "10.1002/anie.200703876",

language = "英语",

volume = "47",

pages = "2646--2648",

journal = "Angewandte Chemie - International Edition",

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T1 - MALDI in-source photooxidation reactions for online peptide tagging

AU - Qiao, Liang

AU - Roussel, Christophe

AU - Wan, Jingjing

AU - Kong, Jilie

AU - Yang, Pengyuan

AU - Girault, Hubert H.

AU - Liu, Baohong

PY - 2008/3/25

Y1 - 2008/3/25

N2 - (Chemical Equation Presented) A TiO2 photoelectrode array has been designed to achieve efficient photoelectrochemical redox reactions with electron donors or acceptors during the laser desorption ionization process. By adding hydroquinone to a peptide mixture, the photoelectrochemically generated benzoquinone reacts with the cysteine residues to selectively form tagged cysteine-containing peptides, thus demonstrating that in-source oxidation reactions can be efficiently performed.

AB - (Chemical Equation Presented) A TiO2 photoelectrode array has been designed to achieve efficient photoelectrochemical redox reactions with electron donors or acceptors during the laser desorption ionization process. By adding hydroquinone to a peptide mixture, the photoelectrochemically generated benzoquinone reacts with the cysteine residues to selectively form tagged cysteine-containing peptides, thus demonstrating that in-source oxidation reactions can be efficiently performed.

KW - Mass spectrometry

KW - Peptides

KW - Photoelectrodes

KW - Photooxidation

KW - Titanium dioxide

UR - https://www.scopus.com/pages/publications/41949094901

U2 - 10.1002/anie.200703876

DO - 10.1002/anie.200703876

M3 - 文章

C2 - 18300219

AN - SCOPUS:41949094901

SN - 1433-7851

VL - 47

SP - 2646

EP - 2648

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 14

ER -

MALDI in-source photooxidation reactions for online peptide tagging

Abstract

Keywords

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