Leukemic cells segmentation algorithm based on molecular spectral imaging technology

  • Qingli Li*
  • , Chunni Dai
  • , Hongjing Liu
  • , Jingao Liu
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

7 Scopus citations

Abstract

A molecular spectral imaging system instead of common microscope was used to capture the spectral images of blood smears. Then an improved spectral angle mapper algorithm for automatic blood cells segmentation was presented. In this algorithm, the spectral vectors of blood cells were normalized first. Then the spectral angles of all bands and partial bands were calculated respectively. Finally, the blood cells were segmented according to the spectral angles combined with the threshold segmentation method. As a case study, the leukemia cells were selected as the target and segmented with the new algorithm. The results demonstrate that this algorithm can utilizes both spectral and spatial information of blood cells and segment the leukemia cells more accurately.

Original languageEnglish
Title of host publicationInternational Symposium on Photoelectronic Detection and Imaging 2009 - Advances in Infrared Imaging and Applications
DOIs
StatePublished - 2009
EventInternational Symposium on Photoelectronic Detection and Imaging 2009: Advances in Infrared Imaging and Applications - Beijing, China
Duration: 17 Jun 200919 Jun 2009

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume7383
ISSN (Print)0277-786X

Conference

ConferenceInternational Symposium on Photoelectronic Detection and Imaging 2009: Advances in Infrared Imaging and Applications
Country/TerritoryChina
CityBeijing
Period17/06/0919/06/09

Keywords

  • Biomedical imaging
  • Image segmentation
  • Leukemia cells
  • Spectral angle mapper
  • Spectral imaging

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