Let's turn the CAR-T cells ON and OFF precisely

Jiqin Zhang; Bing Du; Mingyao Liu

doi:10.1016/j.ccell.2022.10.019

Let's turn the CAR-T cells ON and OFF precisely

Jiqin Zhang^*
, Bing Du
, Mingyao Liu^*

^*Corresponding author for this work

School of Life Sciences

Research output: Contribution to journal › Comment/debate

6 Scopus citations

Abstract

In this issue of Cancer Cell, Li et al. develop novel tunable ON/OFF switch chimeric antigen receptor (CAR) circuits using clinically approved drugs based on the viral NS3 protease system. These platforms not only show superior controllability but also have high performance and compatibility, thereby providing versatile tools for precisely modulating CAR-T cells.

Original language	English
Pages (from-to)	1264-1266
Number of pages	3
Journal	Cancer Cell
Volume	40
Issue number	11
DOIs	https://doi.org/10.1016/j.ccell.2022.10.019
State	Published - 14 Nov 2022

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10.1016/j.ccell.2022.10.019

Cite this

@article{10aa16f14e044fbca9b35f1dfd2646ad,

title = "Let's turn the CAR-T cells ON and OFF precisely",

abstract = "In this issue of Cancer Cell, Li et al. develop novel tunable ON/OFF switch chimeric antigen receptor (CAR) circuits using clinically approved drugs based on the viral NS3 protease system. These platforms not only show superior controllability but also have high performance and compatibility, thereby providing versatile tools for precisely modulating CAR-T cells.",

author = "Jiqin Zhang and Bing Du and Mingyao Liu",

note = "Publisher Copyright: {\textcopyright} 2022 Elsevier Inc.",

year = "2022",

month = nov,

day = "14",

doi = "10.1016/j.ccell.2022.10.019",

language = "英语",

volume = "40",

pages = "1264--1266",

journal = "Cancer Cell",

issn = "1535-6108",

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}

TY - JOUR

T1 - Let's turn the CAR-T cells ON and OFF precisely

AU - Zhang, Jiqin

AU - Du, Bing

AU - Liu, Mingyao

PY - 2022/11/14

Y1 - 2022/11/14

N2 - In this issue of Cancer Cell, Li et al. develop novel tunable ON/OFF switch chimeric antigen receptor (CAR) circuits using clinically approved drugs based on the viral NS3 protease system. These platforms not only show superior controllability but also have high performance and compatibility, thereby providing versatile tools for precisely modulating CAR-T cells.

AB - In this issue of Cancer Cell, Li et al. develop novel tunable ON/OFF switch chimeric antigen receptor (CAR) circuits using clinically approved drugs based on the viral NS3 protease system. These platforms not only show superior controllability but also have high performance and compatibility, thereby providing versatile tools for precisely modulating CAR-T cells.

UR - https://www.scopus.com/pages/publications/85141960664

U2 - 10.1016/j.ccell.2022.10.019

DO - 10.1016/j.ccell.2022.10.019

M3 - 评论/辩论

C2 - 36379203

AN - SCOPUS:85141960664

SN - 1535-6108

VL - 40

SP - 1264

EP - 1266

JO - Cancer Cell

JF - Cancer Cell

IS - 11

ER -

Let's turn the CAR-T cells ON and OFF precisely

Abstract

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