Laser reshaping of gold nanoparticles for highly sensitive SERS detection of ciprofloxacin

  • Ao Zhang
  • , Jijun Feng*
  • , Jingci Yan
  • , Mengyun Hu
  • , Ling Zhang
  • , Heping Zeng
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Laser reshaping of hexagonal gold plates is demonstrated to generate particles with different size and shape, which is further used for highly sensitive label-free surface-enhanced Raman scattering detection of synthetic antibiotic ciprofloxacin. A nanosecond laser can be used to reshape gold particles to 120-nm diameter and form a spherical-hexagonal combined structure, while a femtosecond laser can reshape the particles into spherical and triangle shapes with an average size of 6 nm. The nano-sized particles can help to enhance the Raman signal and demonstrate a superior performance with a lowest detection limit of 7.5 × 10−8 M for the ciprofloxacin sensing in milk. The presented ultrafast laser reshaping of gold nanoparticles can be exploited in a wide range of plasmonic enhanced sensing applications for a simple, fast, flexible, and portable biomaterial detection.

Original languageEnglish
Article number152543
JournalApplied Surface Science
Volume583
DOIs
StatePublished - 1 May 2022

Keywords

  • Ciprofloxacin
  • Gold nanoparticles
  • Laser reshaping
  • Surface-enhanced Raman scattering

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