KiSS1 and its G-protein-coupled receptor GPR54 in cancer development and metastasis

Sung Gook Cho; Dali Li; Kunrong Tan; Stefan K. Siwko; Mingyao Liu

doi:10.1007/s10555-012-9367-7

KiSS1 and its G-protein-coupled receptor GPR54 in cancer development and metastasis

Sung Gook Cho
, Dali Li
, Kunrong Tan
, Stefan K. Siwko
, Mingyao Liu^*

^*Corresponding author for this work

School of Life Sciences

Texas A&M University

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

KiSS1 and its cognate G-protein-coupled receptor, GPR54, have diverse functions. While KiSS1 and GPR54 have been intensively studied in physiology, their role in cancer is still unclear. In cancer, KiSS1 and GPR54 have been known to suppress metastasis by inhibiting cancer cell motility. However, recent studies suggest that KiSS1 and GPR54 have varied roles even in cancer development and metastasis. Here, we examine recent advances in understanding the roles of KiSS1 and GPR54 in cancer development and metastasis.

Original language	English
Pages (from-to)	585-591
Number of pages	7
Journal	Cancer and Metastasis Reviews
Volume	31
Issue number	3-4
DOIs	https://doi.org/10.1007/s10555-012-9367-7
State	Published - Dec 2012

Keywords

Cancer
GPR54
KiSS1
Kisspeptin
Metastasis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s10555-012-9367-7

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title = "KiSS1 and its G-protein-coupled receptor GPR54 in cancer development and metastasis",

abstract = "KiSS1 and its cognate G-protein-coupled receptor, GPR54, have diverse functions. While KiSS1 and GPR54 have been intensively studied in physiology, their role in cancer is still unclear. In cancer, KiSS1 and GPR54 have been known to suppress metastasis by inhibiting cancer cell motility. However, recent studies suggest that KiSS1 and GPR54 have varied roles even in cancer development and metastasis. Here, we examine recent advances in understanding the roles of KiSS1 and GPR54 in cancer development and metastasis.",

keywords = "Cancer, GPR54, KiSS1, Kisspeptin, Metastasis",

author = "Cho, \{Sung Gook\} and Dali Li and Kunrong Tan and Siwko, \{Stefan K.\} and Mingyao Liu",

year = "2012",

month = dec,

doi = "10.1007/s10555-012-9367-7",

language = "英语",

volume = "31",

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journal = "Cancer and Metastasis Reviews",

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TY - JOUR

T1 - KiSS1 and its G-protein-coupled receptor GPR54 in cancer development and metastasis

AU - Cho, Sung Gook

AU - Li, Dali

AU - Tan, Kunrong

AU - Siwko, Stefan K.

AU - Liu, Mingyao

PY - 2012/12

Y1 - 2012/12

N2 - KiSS1 and its cognate G-protein-coupled receptor, GPR54, have diverse functions. While KiSS1 and GPR54 have been intensively studied in physiology, their role in cancer is still unclear. In cancer, KiSS1 and GPR54 have been known to suppress metastasis by inhibiting cancer cell motility. However, recent studies suggest that KiSS1 and GPR54 have varied roles even in cancer development and metastasis. Here, we examine recent advances in understanding the roles of KiSS1 and GPR54 in cancer development and metastasis.

AB - KiSS1 and its cognate G-protein-coupled receptor, GPR54, have diverse functions. While KiSS1 and GPR54 have been intensively studied in physiology, their role in cancer is still unclear. In cancer, KiSS1 and GPR54 have been known to suppress metastasis by inhibiting cancer cell motility. However, recent studies suggest that KiSS1 and GPR54 have varied roles even in cancer development and metastasis. Here, we examine recent advances in understanding the roles of KiSS1 and GPR54 in cancer development and metastasis.

KW - Cancer

KW - GPR54

KW - KiSS1

KW - Kisspeptin

KW - Metastasis

UR - https://www.scopus.com/pages/publications/84868002638

U2 - 10.1007/s10555-012-9367-7

DO - 10.1007/s10555-012-9367-7

M3 - 文章

C2 - 22692479

AN - SCOPUS:84868002638

SN - 0167-7659

VL - 31

SP - 585

EP - 591

JO - Cancer and Metastasis Reviews

JF - Cancer and Metastasis Reviews

IS - 3-4

ER -

KiSS1 and its G-protein-coupled receptor GPR54 in cancer development and metastasis

Abstract

Keywords

UN SDGs

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