Kinetically Controlled Dendritic Mesoporous Silica Nanoparticles: From Dahlia- to Pomegranate-like Structures by Micelle Filling

Yue Wang; Hao Song; Yannan Yang; Yang Liu; Jie Tang; Chengzhong Yu

doi:10.1021/acs.chemmater.8b02712

Kinetically Controlled Dendritic Mesoporous Silica Nanoparticles: From Dahlia- to Pomegranate-like Structures by Micelle Filling

Yue Wang
, Hao Song
, Yannan Yang
, Yang Liu
, Jie Tang
, Chengzhong Yu^*

^*Corresponding author for this work

University of Queensland

Research output: Contribution to journal › Article › peer-review

56 Scopus citations

Abstract

A unique dynamic structural transition from large-pore dendritic mesoporous silica nanoparticles (DMSNs) with a dahlia-like morphology to pomegranate-like mesoporous silica nanoparticles with small mesopores is reported. The structural evolution is accompanied by gradually filling the preformed dendritic large pores with silica-coated micelles, providing a series of DMSNs with kinetically controlled dual mesoporosity. The heterogeneous porous structure of DMSNs demonstrates advantages in the co-loading of two positively charged drug molecules, showing promising potential in cellular delivery applications.

Original language	English
Pages (from-to)	5770-5776
Number of pages	7
Journal	Chemistry of Materials
Volume	30
Issue number	16
DOIs	https://doi.org/10.1021/acs.chemmater.8b02712
State	Published - 28 Aug 2018
Externally published	Yes

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title = "Kinetically Controlled Dendritic Mesoporous Silica Nanoparticles: From Dahlia- to Pomegranate-like Structures by Micelle Filling",

abstract = "A unique dynamic structural transition from large-pore dendritic mesoporous silica nanoparticles (DMSNs) with a dahlia-like morphology to pomegranate-like mesoporous silica nanoparticles with small mesopores is reported. The structural evolution is accompanied by gradually filling the preformed dendritic large pores with silica-coated micelles, providing a series of DMSNs with kinetically controlled dual mesoporosity. The heterogeneous porous structure of DMSNs demonstrates advantages in the co-loading of two positively charged drug molecules, showing promising potential in cellular delivery applications.",

author = "Yue Wang and Hao Song and Yannan Yang and Yang Liu and Jie Tang and Chengzhong Yu",

note = "Publisher Copyright: {\textcopyright} 2018 American Chemical Society.",

year = "2018",

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doi = "10.1021/acs.chemmater.8b02712",

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T1 - Kinetically Controlled Dendritic Mesoporous Silica Nanoparticles

T2 - From Dahlia- to Pomegranate-like Structures by Micelle Filling

AU - Wang, Yue

AU - Song, Hao

AU - Yang, Yannan

AU - Liu, Yang

AU - Tang, Jie

AU - Yu, Chengzhong

PY - 2018/8/28

Y1 - 2018/8/28

N2 - A unique dynamic structural transition from large-pore dendritic mesoporous silica nanoparticles (DMSNs) with a dahlia-like morphology to pomegranate-like mesoporous silica nanoparticles with small mesopores is reported. The structural evolution is accompanied by gradually filling the preformed dendritic large pores with silica-coated micelles, providing a series of DMSNs with kinetically controlled dual mesoporosity. The heterogeneous porous structure of DMSNs demonstrates advantages in the co-loading of two positively charged drug molecules, showing promising potential in cellular delivery applications.

AB - A unique dynamic structural transition from large-pore dendritic mesoporous silica nanoparticles (DMSNs) with a dahlia-like morphology to pomegranate-like mesoporous silica nanoparticles with small mesopores is reported. The structural evolution is accompanied by gradually filling the preformed dendritic large pores with silica-coated micelles, providing a series of DMSNs with kinetically controlled dual mesoporosity. The heterogeneous porous structure of DMSNs demonstrates advantages in the co-loading of two positively charged drug molecules, showing promising potential in cellular delivery applications.

UR - https://www.scopus.com/pages/publications/85052630415

U2 - 10.1021/acs.chemmater.8b02712

DO - 10.1021/acs.chemmater.8b02712

M3 - 文章

AN - SCOPUS:85052630415

SN - 0897-4756

VL - 30

SP - 5770

EP - 5776

JO - Chemistry of Materials

JF - Chemistry of Materials

IS - 16

ER -

Kinetically Controlled Dendritic Mesoporous Silica Nanoparticles: From Dahlia- to Pomegranate-like Structures by Micelle Filling

Abstract

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