TY - JOUR
T1 - Kinetically Controlled Dendritic Mesoporous Silica Nanoparticles
T2 - From Dahlia- to Pomegranate-like Structures by Micelle Filling
AU - Wang, Yue
AU - Song, Hao
AU - Yang, Yannan
AU - Liu, Yang
AU - Tang, Jie
AU - Yu, Chengzhong
N1 - Publisher Copyright:
© 2018 American Chemical Society.
PY - 2018/8/28
Y1 - 2018/8/28
N2 - A unique dynamic structural transition from large-pore dendritic mesoporous silica nanoparticles (DMSNs) with a dahlia-like morphology to pomegranate-like mesoporous silica nanoparticles with small mesopores is reported. The structural evolution is accompanied by gradually filling the preformed dendritic large pores with silica-coated micelles, providing a series of DMSNs with kinetically controlled dual mesoporosity. The heterogeneous porous structure of DMSNs demonstrates advantages in the co-loading of two positively charged drug molecules, showing promising potential in cellular delivery applications.
AB - A unique dynamic structural transition from large-pore dendritic mesoporous silica nanoparticles (DMSNs) with a dahlia-like morphology to pomegranate-like mesoporous silica nanoparticles with small mesopores is reported. The structural evolution is accompanied by gradually filling the preformed dendritic large pores with silica-coated micelles, providing a series of DMSNs with kinetically controlled dual mesoporosity. The heterogeneous porous structure of DMSNs demonstrates advantages in the co-loading of two positively charged drug molecules, showing promising potential in cellular delivery applications.
UR - https://www.scopus.com/pages/publications/85052630415
U2 - 10.1021/acs.chemmater.8b02712
DO - 10.1021/acs.chemmater.8b02712
M3 - 文章
AN - SCOPUS:85052630415
SN - 0897-4756
VL - 30
SP - 5770
EP - 5776
JO - Chemistry of Materials
JF - Chemistry of Materials
IS - 16
ER -