Iridium-catalyzed highly enantioselective hydrogenation of exocyclic α,β-unsaturated carbonyl compounds

Fengtao Tian; Dongmei Yao; Yuanyuan Liu; Fang Xie; Wanbin Zhang

doi:10.1002/adsc.201000185

Iridium-catalyzed highly enantioselective hydrogenation of exocyclic α,β-unsaturated carbonyl compounds

Fengtao Tian, Dongmei Yao, Yuanyuan Liu, Fang Xie, Wanbin Zhang

Shanghai Jiao Tong University

Research output: Contribution to journal › Article › peer-review

101 Scopus citations

Abstract

By using the iridium complex of a phosphine-oxazoline ligand with an axis-unfixed biphenyl backbone, a highly enantioselective hydrogenation of the C=C bond of exocyclic α,β-unsaturated carbonyl compounds to afford α-chiral cyclic ketones, lactones and lactams was developed.

Original language	English
Pages (from-to)	1841-1845
Number of pages	5
Journal	Advanced Synthesis and Catalysis
Volume	352
Issue number	11-12
DOIs	https://doi.org/10.1002/adsc.201000185
State	Published - 2010
Externally published	Yes

Keywords

Asymmetric synthesis
Cyclic carbonyl compounds
Hydrogenation
Iridium
Oxazoline

Access to Document

10.1002/adsc.201000185

Cite this

@article{db907c155dd3413681401a2196493dc4,

title = "Iridium-catalyzed highly enantioselective hydrogenation of exocyclic α,β-unsaturated carbonyl compounds",

abstract = "By using the iridium complex of a phosphine-oxazoline ligand with an axis-unfixed biphenyl backbone, a highly enantioselective hydrogenation of the C=C bond of exocyclic α,β-unsaturated carbonyl compounds to afford α-chiral cyclic ketones, lactones and lactams was developed.",

keywords = "Asymmetric synthesis, Cyclic carbonyl compounds, Hydrogenation, Iridium, Oxazoline",

author = "Fengtao Tian and Dongmei Yao and Yuanyuan Liu and Fang Xie and Wanbin Zhang",

year = "2010",

doi = "10.1002/adsc.201000185",

language = "英语",

volume = "352",

pages = "1841--1845",

journal = "Advanced Synthesis and Catalysis",

issn = "1615-4150",

publisher = "Wiley-VCH Verlag",

number = "11-12",

}

TY - JOUR

T1 - Iridium-catalyzed highly enantioselective hydrogenation of exocyclic α,β-unsaturated carbonyl compounds

AU - Tian, Fengtao

AU - Yao, Dongmei

AU - Liu, Yuanyuan

AU - Xie, Fang

AU - Zhang, Wanbin

PY - 2010

Y1 - 2010

N2 - By using the iridium complex of a phosphine-oxazoline ligand with an axis-unfixed biphenyl backbone, a highly enantioselective hydrogenation of the C=C bond of exocyclic α,β-unsaturated carbonyl compounds to afford α-chiral cyclic ketones, lactones and lactams was developed.

AB - By using the iridium complex of a phosphine-oxazoline ligand with an axis-unfixed biphenyl backbone, a highly enantioselective hydrogenation of the C=C bond of exocyclic α,β-unsaturated carbonyl compounds to afford α-chiral cyclic ketones, lactones and lactams was developed.

KW - Asymmetric synthesis

KW - Cyclic carbonyl compounds

KW - Hydrogenation

KW - Iridium

KW - Oxazoline

UR - https://www.scopus.com/pages/publications/77956371581

U2 - 10.1002/adsc.201000185

DO - 10.1002/adsc.201000185

M3 - 文章

AN - SCOPUS:77956371581

SN - 1615-4150

VL - 352

SP - 1841

EP - 1845

JO - Advanced Synthesis and Catalysis

JF - Advanced Synthesis and Catalysis

IS - 11-12

ER -

Iridium-catalyzed highly enantioselective hydrogenation of exocyclic α,β-unsaturated carbonyl compounds

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this