Iridium-Catalyzed Asymmetric C-H Borylation Enabled by Chiral Bidentate Boryl Ligands

Asymmetric synthesis of optically pure organoboron compounds is a topic that has received a number of attentions owing to their particular importance in synthetic chemistry and drug discovery. We herein highlight recent advances in the iridium-catalyzed C-H borylation of diarylmethylamines and cyclopropanes enabled by chiral bidentate boryl ligands. 1 Introduction 2 Ir-Catalyzed Asymmetric C(sp ²)-H Borylation of Diarylmethylamines 3 Ir-Catalyzed Enantioselective C(sp ³)-H Borylation of Cyclopropanes 4 Conclusion.