Iridium-catalysed branched-selective hydroacylation of 1,3-dienes with salicylaldehydes

Yang Yang; Dong Xing

doi:10.1039/d1cc01872h

Iridium-catalysed branched-selective hydroacylation of 1,3-dienes with salicylaldehydes

Yang Yang
, Dong Xing^*

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Herein, we report an iridium-catalyzed branched-selective hydroacylation of 1-aryl 1,3-dienes with salicylaldehydes under mild conditions with no need of phosphine ligands. With this protocol, a series of α-branched β,γ-unsaturatedo-hydroxyacetophenones with biological potentials were synthesized in high efficiency with excellent regioselectivities. When simple 1,3-butadiene or isoprene instead of 1-aryl 1,3-dienes were used, exclusive linear-selective hydroacylation products were obtained.

Original language	English
Pages (from-to)	7378-7381
Number of pages	4
Journal	Chemical Communications
Volume	57
Issue number	60
DOIs	https://doi.org/10.1039/d1cc01872h
State	Published - 4 Aug 2021

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title = "Iridium-catalysed branched-selective hydroacylation of 1,3-dienes with salicylaldehydes",

abstract = "Herein, we report an iridium-catalyzed branched-selective hydroacylation of 1-aryl 1,3-dienes with salicylaldehydes under mild conditions with no need of phosphine ligands. With this protocol, a series of α-branched β,γ-unsaturatedo-hydroxyacetophenones with biological potentials were synthesized in high efficiency with excellent regioselectivities. When simple 1,3-butadiene or isoprene instead of 1-aryl 1,3-dienes were used, exclusive linear-selective hydroacylation products were obtained.",

author = "Yang Yang and Dong Xing",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2021.",

year = "2021",

month = aug,

day = "4",

doi = "10.1039/d1cc01872h",

language = "英语",

volume = "57",

pages = "7378--7381",

journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - Iridium-catalysed branched-selective hydroacylation of 1,3-dienes with salicylaldehydes

AU - Yang, Yang

AU - Xing, Dong

N1 - Publisher Copyright: © The Royal Society of Chemistry 2021.

PY - 2021/8/4

Y1 - 2021/8/4

N2 - Herein, we report an iridium-catalyzed branched-selective hydroacylation of 1-aryl 1,3-dienes with salicylaldehydes under mild conditions with no need of phosphine ligands. With this protocol, a series of α-branched β,γ-unsaturatedo-hydroxyacetophenones with biological potentials were synthesized in high efficiency with excellent regioselectivities. When simple 1,3-butadiene or isoprene instead of 1-aryl 1,3-dienes were used, exclusive linear-selective hydroacylation products were obtained.

AB - Herein, we report an iridium-catalyzed branched-selective hydroacylation of 1-aryl 1,3-dienes with salicylaldehydes under mild conditions with no need of phosphine ligands. With this protocol, a series of α-branched β,γ-unsaturatedo-hydroxyacetophenones with biological potentials were synthesized in high efficiency with excellent regioselectivities. When simple 1,3-butadiene or isoprene instead of 1-aryl 1,3-dienes were used, exclusive linear-selective hydroacylation products were obtained.

UR - https://www.scopus.com/pages/publications/85111408151

U2 - 10.1039/d1cc01872h

DO - 10.1039/d1cc01872h

M3 - 文章

C2 - 34231568

AN - SCOPUS:85111408151

SN - 1359-7345

VL - 57

SP - 7378

EP - 7381

JO - Chemical Communications

JF - Chemical Communications

IS - 60

ER -

Iridium-catalysed branched-selective hydroacylation of 1,3-dienes with salicylaldehydes

Abstract

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