TY - JOUR
T1 - Internal Calibration Potentiometric Aptasensors for Simultaneous Detection of Hg2+, Cd2+, and As3+ Based on a Screen-Printed Carbon Electrodes Array
AU - Tang, Wanxin
AU - Wang, Zhenzhen
AU - Yu, Juan
AU - Zhang, Fan
AU - He, Pingang
N1 - Publisher Copyright:
© 2018 American Chemical Society.
PY - 2018/7/17
Y1 - 2018/7/17
N2 - An all-solid-state potentiometric aptasensor array based on a multichannel disposable screen-printed carbon electrode (SPCE) was demonstrated for the simultaneous detection of Hg2+, Cd2+, and As3+ by open circuit potential (OCP) technology. The potential of the channel with an internal calibration DNA sequence (IC-DNA) was employed as the internal calibration potential (ICP) to subtract the background signal generated by the detection system, providing a built-in correction methodology. As a result, the developed aptasensor array showed high sensitivity and accuracy for detecting Hg2+, Cd2+, and As3+ without mutual interference or interference from other ions. The linear response ranged from 2.5 pM to 2.5 μM, and the detection limits for Hg2+, Cd2+, and As3+ were 2.0, 0.62, and 0.17 pM, respectively. Furthermore, the potentiometric aptasensor array was successfully applied for the simultaneous detection of three ions in real samples. The results obtained from the developed approach agreed well with the results obtained from inductively coupled plasma mass spectrometry.
AB - An all-solid-state potentiometric aptasensor array based on a multichannel disposable screen-printed carbon electrode (SPCE) was demonstrated for the simultaneous detection of Hg2+, Cd2+, and As3+ by open circuit potential (OCP) technology. The potential of the channel with an internal calibration DNA sequence (IC-DNA) was employed as the internal calibration potential (ICP) to subtract the background signal generated by the detection system, providing a built-in correction methodology. As a result, the developed aptasensor array showed high sensitivity and accuracy for detecting Hg2+, Cd2+, and As3+ without mutual interference or interference from other ions. The linear response ranged from 2.5 pM to 2.5 μM, and the detection limits for Hg2+, Cd2+, and As3+ were 2.0, 0.62, and 0.17 pM, respectively. Furthermore, the potentiometric aptasensor array was successfully applied for the simultaneous detection of three ions in real samples. The results obtained from the developed approach agreed well with the results obtained from inductively coupled plasma mass spectrometry.
UR - https://www.scopus.com/pages/publications/85049246904
U2 - 10.1021/acs.analchem.7b04150
DO - 10.1021/acs.analchem.7b04150
M3 - 文章
C2 - 29938501
AN - SCOPUS:85049246904
SN - 0003-2700
VL - 90
SP - 8337
EP - 8344
JO - Analytical Chemistry
JF - Analytical Chemistry
IS - 14
ER -