Intermolecular coupling of alkynes, isocyanates, and acyl chlorides: an efficient method for the synthesis of 5-hydroxypyrrol-2(5H)-ones

Ken ichiro Kanno; Shenyong Ren; Yanzhong Li; Kiyohiko Nakajima; Tamotsu Takahashi

doi:10.1016/j.tetlet.2007.10.096

Intermolecular coupling of alkynes, isocyanates, and acyl chlorides: an efficient method for the synthesis of 5-hydroxypyrrol-2(5H)-ones

Ken ichiro Kanno
, Shenyong Ren
, Yanzhong Li
, Kiyohiko Nakajima
, Tamotsu Takahashi^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

New insights into the reaction of diethylzirconocene with an alkyne, an isocyanate, and an acyl chloride in this order are reported. The products of 5-hydroxypyrrol-2(5H)-ones are obtained in good yields after hydrolysis. It is an efficient method for the synthesis of 5-hydroxypyrrol-2(5H)-ones.

Original language	English
Pages (from-to)	9199-9202
Number of pages	4
Journal	Tetrahedron Letters
Volume	48
Issue number	52
DOIs	https://doi.org/10.1016/j.tetlet.2007.10.096
State	Published - 24 Dec 2007
Externally published	Yes

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title = "Intermolecular coupling of alkynes, isocyanates, and acyl chlorides: an efficient method for the synthesis of 5-hydroxypyrrol-2(5H)-ones",

abstract = "New insights into the reaction of diethylzirconocene with an alkyne, an isocyanate, and an acyl chloride in this order are reported. The products of 5-hydroxypyrrol-2(5H)-ones are obtained in good yields after hydrolysis. It is an efficient method for the synthesis of 5-hydroxypyrrol-2(5H)-ones.",

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journal = "Tetrahedron Letters",

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T1 - Intermolecular coupling of alkynes, isocyanates, and acyl chlorides

T2 - an efficient method for the synthesis of 5-hydroxypyrrol-2(5H)-ones

AU - Kanno, Ken ichiro

AU - Ren, Shenyong

AU - Li, Yanzhong

AU - Nakajima, Kiyohiko

AU - Takahashi, Tamotsu

PY - 2007/12/24

Y1 - 2007/12/24

N2 - New insights into the reaction of diethylzirconocene with an alkyne, an isocyanate, and an acyl chloride in this order are reported. The products of 5-hydroxypyrrol-2(5H)-ones are obtained in good yields after hydrolysis. It is an efficient method for the synthesis of 5-hydroxypyrrol-2(5H)-ones.

AB - New insights into the reaction of diethylzirconocene with an alkyne, an isocyanate, and an acyl chloride in this order are reported. The products of 5-hydroxypyrrol-2(5H)-ones are obtained in good yields after hydrolysis. It is an efficient method for the synthesis of 5-hydroxypyrrol-2(5H)-ones.

UR - https://www.scopus.com/pages/publications/36549014275

U2 - 10.1016/j.tetlet.2007.10.096

DO - 10.1016/j.tetlet.2007.10.096

M3 - 文章

AN - SCOPUS:36549014275

SN - 0040-4039

VL - 48

SP - 9199

EP - 9202

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 52

ER -

Intermolecular coupling of alkynes, isocyanates, and acyl chlorides: an efficient method for the synthesis of 5-hydroxypyrrol-2(5H)-ones

Abstract

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