In vivo monitoring of local pH values in a live rat brain based on the design of a specific electroactive molecule for H+

Fan Zhao; Limin Zhang; Anwei Zhu; Guoyue Shi; Yang Tian

doi:10.1039/c5cc09540a

In vivo monitoring of local pH values in a live rat brain based on the design of a specific electroactive molecule for H⁺

Fan Zhao
, Limin Zhang
, Anwei Zhu
, Guoyue Shi^*
, Yang Tian

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

pH plays an important role in the biochemical, ion-regulatory, or electrical machinery of nerve and glial cells, and is considered to be related to a number of degenerative diseases. Herein, we first develop a two-channel electrochemical ratiometric biosensor for local pH determination in a live rat brain, and report the accurate pH values in the different regions of live brains upon global cerebral ischemia.

Original language	English
Pages (from-to)	3717-3720
Number of pages	4
Journal	Chemical Communications
Volume	52
Issue number	18
DOIs	https://doi.org/10.1039/c5cc09540a
State	Published - 2016

Access to Document

10.1039/c5cc09540a

Cite this

@article{c277ad058b534b46a61707d733ce9b13,

title = "In vivo monitoring of local pH values in a live rat brain based on the design of a specific electroactive molecule for H+",

abstract = "pH plays an important role in the biochemical, ion-regulatory, or electrical machinery of nerve and glial cells, and is considered to be related to a number of degenerative diseases. Herein, we first develop a two-channel electrochemical ratiometric biosensor for local pH determination in a live rat brain, and report the accurate pH values in the different regions of live brains upon global cerebral ischemia.",

author = "Fan Zhao and Limin Zhang and Anwei Zhu and Guoyue Shi and Yang Tian",

note = "Publisher Copyright: {\textcopyright} 2016 The Royal Society of Chemistry.",

year = "2016",

doi = "10.1039/c5cc09540a",

language = "英语",

volume = "52",

pages = "3717--3720",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "18",

}

TY - JOUR

T1 - In vivo monitoring of local pH values in a live rat brain based on the design of a specific electroactive molecule for H+

AU - Zhao, Fan

AU - Zhang, Limin

AU - Zhu, Anwei

AU - Shi, Guoyue

AU - Tian, Yang

PY - 2016

Y1 - 2016

N2 - pH plays an important role in the biochemical, ion-regulatory, or electrical machinery of nerve and glial cells, and is considered to be related to a number of degenerative diseases. Herein, we first develop a two-channel electrochemical ratiometric biosensor for local pH determination in a live rat brain, and report the accurate pH values in the different regions of live brains upon global cerebral ischemia.

AB - pH plays an important role in the biochemical, ion-regulatory, or electrical machinery of nerve and glial cells, and is considered to be related to a number of degenerative diseases. Herein, we first develop a two-channel electrochemical ratiometric biosensor for local pH determination in a live rat brain, and report the accurate pH values in the different regions of live brains upon global cerebral ischemia.

UR - https://www.scopus.com/pages/publications/84959231754

U2 - 10.1039/c5cc09540a

DO - 10.1039/c5cc09540a

M3 - 文章

AN - SCOPUS:84959231754

SN - 1359-7345

VL - 52

SP - 3717

EP - 3720

JO - Chemical Communications

JF - Chemical Communications

IS - 18

ER -

In vivo monitoring of local pH values in a live rat brain based on the design of a specific electroactive molecule for H⁺

Abstract

Access to Document

Other files and links

Fingerprint

Cite this