Hyperhomocysteinemia and kidney diseases

Yun Feng Zhou, You Fei Guan

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

Homocysteine (Hcy) is an intermediate metabolite of methionine metabolism. Hyperhomocysteinemia (HHcy) is defined as a condition characterized by plasma Hcy level above 16 μmol/L which can result from abnormal Hcy metabolism. HHcy has been confirmed to be related to cardio-cerebrovascular disease, peripheral vascular disorders, neurodegenerative diseases, diabetes, pregnancy-induced hypertension syndrome, liver cirrhosis and kidney diseases. In this review, we summarize the correlation between HHcy and kidney diseases. Elucidating the role of HHcy in kidney diseases may provide a new strategy to prevent and treat kidney diseases.

Original languageEnglish
Pages (from-to)607-611
Number of pages5
JournalActa Physiologica Sinica
Volume70
Issue number6
StatePublished - 25 Dec 2018
Externally publishedYes

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