Hybrid laser microfabrication of three-dimensional large-scale fused silica microfluidic chips

Aodong Zhang, Jian Xu, Ming Hu, Xin Li, Xiaolong Li, Jia Qi, Ya Cheng

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Ultrafast laser-assisted etching provides a simple and flexible method for the bonding-free manufacture of glass-based microchannels with three-dimensional (3D) configurations and multiple functionalities. However, when the lengths of the required microchannels reach several centimeters, this method often suffers from manufacturing controllability due to the limitation of etching selectivity. Herein, we demonstrate our progress in 3D manufacturing large-scale fused silica microfluidic chips based on a hybrid laser microfabrication approach, which combines the merits of ultrafast laser-assisted etching and carbon dioxide laser-induced melting. In this approach, extra-access ports are introduced to enhance the homogeneity of laser-fabricated 3D microchannels and subsequently sealed using defocusing carbon dioxide laser irradiation to form all-glass closed microchannels with few inlets and outlets. Moreover, we introduce some important applications of fabricated microfluidic chips.

Original languageEnglish
Title of host publicationLaser-based Micro- and Nanoprocessing XVII
EditorsRainer Kling, Akira Watanabe, Wilhelm Pfleging
PublisherSPIE
ISBN (Electronic)9781510659230
DOIs
StatePublished - 2023
EventLaser-based Micro- and Nanoprocessing XVII 2023 - San Francisco, United States
Duration: 31 Jan 20232 Feb 2023

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume12409
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

ConferenceLaser-based Micro- and Nanoprocessing XVII 2023
Country/TerritoryUnited States
CitySan Francisco
Period31/01/232/02/23

Keywords

  • Ultrafast laser-assisted etching
  • carbon dioxide laser
  • continuous-flow synthesis
  • extra-access ports
  • fused silica
  • glass microchannels
  • microfluidic chips

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