Highly selective and controllable synthesis of arylhydroxylamines by the reduction of nitroarenes with an electron-withdrawing group using a new nitroreductase BaNTR1

Hieu Huy Nguyen-Tran; Gao Wei Zheng; Xu Hong Qian; Jian He Xu

doi:10.1039/c3cc48590k

Highly selective and controllable synthesis of arylhydroxylamines by the reduction of nitroarenes with an electron-withdrawing group using a new nitroreductase BaNTR1

Hieu Huy Nguyen-Tran
, Gao Wei Zheng^*
, Xu Hong Qian
, Jian He Xu

^*Corresponding author for this work

East China University of Science and Technology

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

A new bacterial nitroreductase has been identified and used as a biocatalyst for the controllable reduction of a variety of nitroarenes with an electron-withdrawing group to the corresponding N-arylhydroxylamines under mild reaction conditions with excellent selectivity (>99%). This method therefore represents a green and efficient method for the synthesis of arylhydroxylamines.

Original language	English
Pages (from-to)	2861-2864
Number of pages	4
Journal	Chemical Communications
Volume	50
Issue number	22
DOIs	https://doi.org/10.1039/c3cc48590k
State	Published - 18 Feb 2014
Externally published	Yes

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10.1039/c3cc48590k

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title = "Highly selective and controllable synthesis of arylhydroxylamines by the reduction of nitroarenes with an electron-withdrawing group using a new nitroreductase BaNTR1",

abstract = "A new bacterial nitroreductase has been identified and used as a biocatalyst for the controllable reduction of a variety of nitroarenes with an electron-withdrawing group to the corresponding N-arylhydroxylamines under mild reaction conditions with excellent selectivity (>99\%). This method therefore represents a green and efficient method for the synthesis of arylhydroxylamines.",

author = "Nguyen-Tran, \{Hieu Huy\} and Zheng, \{Gao Wei\} and Qian, \{Xu Hong\} and Xu, \{Jian He\}",

year = "2014",

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doi = "10.1039/c3cc48590k",

language = "英语",

volume = "50",

pages = "2861--2864",

journal = "Chemical Communications",

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T1 - Highly selective and controllable synthesis of arylhydroxylamines by the reduction of nitroarenes with an electron-withdrawing group using a new nitroreductase BaNTR1

AU - Nguyen-Tran, Hieu Huy

AU - Zheng, Gao Wei

AU - Qian, Xu Hong

AU - Xu, Jian He

PY - 2014/2/18

Y1 - 2014/2/18

N2 - A new bacterial nitroreductase has been identified and used as a biocatalyst for the controllable reduction of a variety of nitroarenes with an electron-withdrawing group to the corresponding N-arylhydroxylamines under mild reaction conditions with excellent selectivity (>99%). This method therefore represents a green and efficient method for the synthesis of arylhydroxylamines.

AB - A new bacterial nitroreductase has been identified and used as a biocatalyst for the controllable reduction of a variety of nitroarenes with an electron-withdrawing group to the corresponding N-arylhydroxylamines under mild reaction conditions with excellent selectivity (>99%). This method therefore represents a green and efficient method for the synthesis of arylhydroxylamines.

UR - https://www.scopus.com/pages/publications/84894457402

U2 - 10.1039/c3cc48590k

DO - 10.1039/c3cc48590k

M3 - 文章

C2 - 24488361

AN - SCOPUS:84894457402

SN - 1359-7345

VL - 50

SP - 2861

EP - 2864

JO - Chemical Communications

JF - Chemical Communications

IS - 22

ER -

Highly selective and controllable synthesis of arylhydroxylamines by the reduction of nitroarenes with an electron-withdrawing group using a new nitroreductase BaNTR1

Abstract

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