Highly efficient assembly of 3-hydroxy oxindole scaffold via a catalytic decarboxylative [1,2]-addition strategy

Qiao Ren; Jiayao Huang; Lei Wang; Wenjun Li; Hui Liu; Xuefeng Jiang; Jian Wang

doi:10.1021/cs300628w

Highly efficient assembly of 3-hydroxy oxindole scaffold via a catalytic decarboxylative [1,2]-addition strategy

Qiao Ren
, Jiayao Huang
, Lei Wang
, Wenjun Li
, Hui Liu
, Xuefeng Jiang^*
, Jian Wang

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Abstract

The 3-hydroxy-2-oxindole scaffold is being continuously discovered to be at the core of a diverse set of natural products. Herein, we document a highly efficient catalytic decarboxylative [1,2]-addition strategy to quickly assemble this scaffold, using a catalytic amount of weak base.

Original language	English
Pages (from-to)	2622-2625
Number of pages	4
Journal	ACS Catalysis
Volume	2
Issue number	12
DOIs	https://doi.org/10.1021/cs300628w
State	Published - 7 Dec 2012

Keywords

1,2-addition
decarboxylation
organocatalysis
oxindole

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10.1021/cs300628w

Cite this

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title = "Highly efficient assembly of 3-hydroxy oxindole scaffold via a catalytic decarboxylative [1,2]-addition strategy",

abstract = "The 3-hydroxy-2-oxindole scaffold is being continuously discovered to be at the core of a diverse set of natural products. Herein, we document a highly efficient catalytic decarboxylative [1,2]-addition strategy to quickly assemble this scaffold, using a catalytic amount of weak base.",

keywords = "1,2-addition, decarboxylation, organocatalysis, oxindole",

author = "Qiao Ren and Jiayao Huang and Lei Wang and Wenjun Li and Hui Liu and Xuefeng Jiang and Jian Wang",

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journal = "ACS Catalysis",

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T1 - Highly efficient assembly of 3-hydroxy oxindole scaffold via a catalytic decarboxylative [1,2]-addition strategy

AU - Ren, Qiao

AU - Huang, Jiayao

AU - Wang, Lei

AU - Li, Wenjun

AU - Liu, Hui

AU - Jiang, Xuefeng

AU - Wang, Jian

PY - 2012/12/7

Y1 - 2012/12/7

N2 - The 3-hydroxy-2-oxindole scaffold is being continuously discovered to be at the core of a diverse set of natural products. Herein, we document a highly efficient catalytic decarboxylative [1,2]-addition strategy to quickly assemble this scaffold, using a catalytic amount of weak base.

AB - The 3-hydroxy-2-oxindole scaffold is being continuously discovered to be at the core of a diverse set of natural products. Herein, we document a highly efficient catalytic decarboxylative [1,2]-addition strategy to quickly assemble this scaffold, using a catalytic amount of weak base.

KW - 1,2-addition

KW - decarboxylation

KW - organocatalysis

KW - oxindole

UR - https://www.scopus.com/pages/publications/84870930078

U2 - 10.1021/cs300628w

DO - 10.1021/cs300628w

M3 - 文章

AN - SCOPUS:84870930078

SN - 2155-5435

VL - 2

SP - 2622

EP - 2625

JO - ACS Catalysis

JF - ACS Catalysis

IS - 12

ER -

Highly efficient assembly of 3-hydroxy oxindole scaffold via a catalytic decarboxylative [1,2]-addition strategy

Abstract

Keywords

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