Highly biocompatible, hollow coordination polymer nanoparticles as cisplatin carriers for efficient intracellular drug delivery

Hong Yuan Lian; Ming Hu; Chia Hung Liu; Yusuke Yamauchi; Kevin C.W. Wu

doi:10.1039/c2cc31708g

Highly biocompatible, hollow coordination polymer nanoparticles as cisplatin carriers for efficient intracellular drug delivery

Hong Yuan Lian
, Ming Hu
, Chia Hung Liu
, Yusuke Yamauchi
, Kevin C.W. Wu^*

^*Corresponding author for this work

National Taiwan University
National Institute for Materials Science Tsukuba
Taipei Medical University
Waseda University
National Health Research Institutes Taiwan

Research output: Contribution to journal › Article › peer-review

172 Scopus citations

Abstract

Highly biocompatible coordination polymer (Prussian Blue) nanoparticles (LC₅₀ > 1000 μg mL⁻¹) with a hollow interior and a microporous framework (denoted as HPB) are utilized as an anticancer drug (i.e. cisplatin) capsule for chemotherapy of bladder cancer T24 cells.

Original language	English
Pages (from-to)	5151-5153
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	42
DOIs	https://doi.org/10.1039/c2cc31708g
State	Published - 30 Apr 2012
Externally published	Yes

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1039/c2cc31708g

Cite this

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title = "Highly biocompatible, hollow coordination polymer nanoparticles as cisplatin carriers for efficient intracellular drug delivery",

abstract = "Highly biocompatible coordination polymer (Prussian Blue) nanoparticles (LC50 > 1000 μg mL−1) with a hollow interior and a microporous framework (denoted as HPB) are utilized as an anticancer drug (i.e. cisplatin) capsule for chemotherapy of bladder cancer T24 cells.",

author = "Lian, \{Hong Yuan\} and Ming Hu and Liu, \{Chia Hung\} and Yusuke Yamauchi and Wu, \{Kevin C.W.\}",

year = "2012",

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doi = "10.1039/c2cc31708g",

language = "英语",

volume = "48",

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T1 - Highly biocompatible, hollow coordination polymer nanoparticles as cisplatin carriers for efficient intracellular drug delivery

AU - Lian, Hong Yuan

AU - Hu, Ming

AU - Liu, Chia Hung

AU - Yamauchi, Yusuke

AU - Wu, Kevin C.W.

PY - 2012/4/30

Y1 - 2012/4/30

N2 - Highly biocompatible coordination polymer (Prussian Blue) nanoparticles (LC50 > 1000 μg mL−1) with a hollow interior and a microporous framework (denoted as HPB) are utilized as an anticancer drug (i.e. cisplatin) capsule for chemotherapy of bladder cancer T24 cells.

AB - Highly biocompatible coordination polymer (Prussian Blue) nanoparticles (LC50 > 1000 μg mL−1) with a hollow interior and a microporous framework (denoted as HPB) are utilized as an anticancer drug (i.e. cisplatin) capsule for chemotherapy of bladder cancer T24 cells.

UR - https://www.scopus.com/pages/publications/84860386168

U2 - 10.1039/c2cc31708g

DO - 10.1039/c2cc31708g

M3 - 文章

C2 - 22514015

AN - SCOPUS:84860386168

SN - 1359-7345

VL - 48

SP - 5151

EP - 5153

JO - Chemical Communications

JF - Chemical Communications

IS - 42

ER -

Highly biocompatible, hollow coordination polymer nanoparticles as cisplatin carriers for efficient intracellular drug delivery

Abstract

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