High-resolution 14N-edited 1H-13C correlation NMR experiment to study biological solids

Jean Paul Amoureux; Julien Trébosc; Bingwen Hu; Nicholas Halpern-Manners; Sasa Antonijevic

doi:10.1016/j.jmr.2008.07.021

High-resolution ¹⁴N-edited ¹H-¹³C correlation NMR experiment to study biological solids

Jean Paul Amoureux^*
, Julien Trébosc
, Bingwen Hu
, Nicholas Halpern-Manners
, Sasa Antonijevic

^*Corresponding author for this work

Bât. C7
University of California at Berkeley
Lawrence Berkeley National Laboratory

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

It was recently shown that nuclear magnetic resonance (NMR) spectra of nitrogen-14 (spin I = 1) can be obtained by indirect detection via spin S = 1/2 nuclei in powders spinning at the magic angle. An increased number of solid-state NMR methods are now available to tailor sequences for specific purposes, e.g., hetero-nuclear dipolar recoupling or homo-nuclear dipolar decoupling schemes. Here, we combine the latest recoupling and decoupling techniques to obtain high-resolution ¹H-¹³C through-space correlation spectra, where only the correlation peaks of those carbons close to nitrogen nuclei are observed. The experiment is demonstrated on a ¹³C enriched l-histidine. HCl·H₂O powder sample.

Original language	English
Pages (from-to)	317-320
Number of pages	4
Journal	Journal of Magnetic Resonance
Volume	194
Issue number	2
DOIs	https://doi.org/10.1016/j.jmr.2008.07.021
State	Published - Oct 2008
Externally published	Yes

Keywords

2D correlation
Amino acids
Coherence transfer
Nitrogen-14
Solid-state NMR

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10.1016/j.jmr.2008.07.021

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title = "High-resolution 14N-edited 1H-13C correlation NMR experiment to study biological solids",

abstract = "It was recently shown that nuclear magnetic resonance (NMR) spectra of nitrogen-14 (spin I = 1) can be obtained by indirect detection via spin S = 1/2 nuclei in powders spinning at the magic angle. An increased number of solid-state NMR methods are now available to tailor sequences for specific purposes, e.g., hetero-nuclear dipolar recoupling or homo-nuclear dipolar decoupling schemes. Here, we combine the latest recoupling and decoupling techniques to obtain high-resolution 1H-13C through-space correlation spectra, where only the correlation peaks of those carbons close to nitrogen nuclei are observed. The experiment is demonstrated on a 13C enriched l-histidine. HCl·H2O powder sample.",

keywords = "2D correlation, Amino acids, Coherence transfer, Nitrogen-14, Solid-state NMR",

author = "Amoureux, \{Jean Paul\} and Julien Tr{\'e}bosc and Bingwen Hu and Nicholas Halpern-Manners and Sasa Antonijevic",

year = "2008",

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T1 - High-resolution 14N-edited 1H-13C correlation NMR experiment to study biological solids

AU - Amoureux, Jean Paul

AU - Trébosc, Julien

AU - Hu, Bingwen

AU - Halpern-Manners, Nicholas

AU - Antonijevic, Sasa

PY - 2008/10

Y1 - 2008/10

N2 - It was recently shown that nuclear magnetic resonance (NMR) spectra of nitrogen-14 (spin I = 1) can be obtained by indirect detection via spin S = 1/2 nuclei in powders spinning at the magic angle. An increased number of solid-state NMR methods are now available to tailor sequences for specific purposes, e.g., hetero-nuclear dipolar recoupling or homo-nuclear dipolar decoupling schemes. Here, we combine the latest recoupling and decoupling techniques to obtain high-resolution 1H-13C through-space correlation spectra, where only the correlation peaks of those carbons close to nitrogen nuclei are observed. The experiment is demonstrated on a 13C enriched l-histidine. HCl·H2O powder sample.

AB - It was recently shown that nuclear magnetic resonance (NMR) spectra of nitrogen-14 (spin I = 1) can be obtained by indirect detection via spin S = 1/2 nuclei in powders spinning at the magic angle. An increased number of solid-state NMR methods are now available to tailor sequences for specific purposes, e.g., hetero-nuclear dipolar recoupling or homo-nuclear dipolar decoupling schemes. Here, we combine the latest recoupling and decoupling techniques to obtain high-resolution 1H-13C through-space correlation spectra, where only the correlation peaks of those carbons close to nitrogen nuclei are observed. The experiment is demonstrated on a 13C enriched l-histidine. HCl·H2O powder sample.

KW - 2D correlation

KW - Amino acids

KW - Coherence transfer

KW - Nitrogen-14

KW - Solid-state NMR

UR - https://www.scopus.com/pages/publications/52949092445

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DO - 10.1016/j.jmr.2008.07.021

M3 - 文章

C2 - 18707905

AN - SCOPUS:52949092445

SN - 1090-7807

VL - 194

SP - 317

EP - 320

JO - Journal of Magnetic Resonance

JF - Journal of Magnetic Resonance

IS - 2

ER -

High-resolution ¹⁴N-edited ¹H-¹³C correlation NMR experiment to study biological solids

Abstract

Keywords

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